摘要
目的 :研究血清癌胚抗原 (CEA)、β2-微球蛋白 (β2-MG)和血清铁蛋白 (SF)测定对大肠癌诊断的临床价值。方法 :采用放射免疫法(RIA)检测31例大肠癌患者和30例结肠炎患者血清CEA、β2-MG、SF的含量。结果 :大肠癌3项标记物测定值均明显高于对照组 (P<0.01),3项标记物联合检测 ,其敏感性、特异性和诊断准确率分别为90.3 %、76.6 %、83.6%。结论 :血清CEA、β2-MG、SF测定对大肠癌诊断具有临床意义 ,3项标记物联合检测可提高大肠癌诊断的敏感性和诊断准确率。
objective: To study the clinical value of serum CEA, β2-MG and SF determination in the diagnosis of colorectal cancer. Method: serum markers CEA, β2-MG and SF contents of 31 cases of patients with colorectal cancer and 30 cases with colitis were determined by radioimmunoassay . Results: the levels of serum makers in the cancer group were significantly higher than that the control ( P<0.01). When the three cancer markers were determined by combined examination, the rates of sensitivity, specificity and diagnostic accuracy were 90.3%, 76.6% and 83.6% respectively. Conclusion: the determinations of serum CEA, β2-MG and SF contents have clinically significance in the diagnosis of colorectal cancer. The combined examination may increase the sensitivity and diagnostic rate for colorectal cancer.
出处
《海南医学院学报》
CAS
2000年第4期209-211,共3页
Journal of Hainan Medical University
