摘要
目的分组比较肺癌、肝癌及肠癌患者与正常体检人群之间血清胆一微球蛋白（β2-MG）的不同，并探讨β2-MG对不同恶性肿瘤诊断的临床价值。方法用电化学发光法测定不同年龄正常体检组及不同年龄不同类型肿瘤人群组的血清β2-MG，并对结果进行统计学分析。结果正常体检组中，不同的年龄段血清中β2-MG的含量存在一定的生理性差异。同一年龄段，肿瘤人群组血清中的β2-MG的含量明显高于正常人群组。三种肿瘤人群纽中，血清中的β2-MG的含量均高于正常人群组，但肝癌组血清中β2-MG的含量最高。结论血清中β2-MG的舍量随着受检者年龄的增长而有一定的生理性改变，β2-MG作为一个恶性肿瘤相关的血液学检查，其对相关肿瘤的辅助诊断有一定的临床意义。
Objective To compare of β2-microglobulin （β2-MG） level between health examination normal population and group of lung cancer,liver cancer and eoloreetal cancer. To discusslβ2-MG chnical value for diagnosis of malignant tumor. Methods To detect β2-MG of digerent age normal population groups and different types of cancer group use use chemiluminescence principle. and the results were statistically analyzed. Results In health examination normal population group, the β2- MG levels of dffterent age groups there are some physiological dif-ferences. The same age part, the β2-MG levels of tumor population groups were significantly higher than the normal population group. People in the three tumor groups, serum β2-MG levels were higher than the normal group, but liver cancer serum β2-MG levels in the highest. Conclusion β2-MG in serum levels with age have a certain degree of physiological changes, β2-MG as the diagnosis of a malignanl hema-tology program, its related cancer diagnostic marker has clinical value.
出处
《医学检验与临床》
2012年第3期15-17,共3页
Medical Laboratory Science and Clinics
