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不同促排卵方案用于宫腔内人工授精临床结局比较 被引量：11

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摘要 目的比较不同促排卵方案用于宫腔内人工授精(IUI)的临床结局。方法回顾性分析589例不孕症患者行1 238个周期宫腔内人工授精的临床资料,对自然周期(NC)人工授精及氯米芬(CC)、氯米芬/尿促性素(CC/HMG)、来曲唑(LE)、来曲唑/尿促性素(LE/HMG)、尿促性素(HMG)促排卵方案行宫腔内人工授精的临床结局进行比较分析。结果 NC、CC、CC/HMG、LE、LE/HMG、HMG临床妊娠率分别为9.98%、13.46%、15.96%、21.21%、23.75%、15.14%,促排卵妊娠率均高于NC(P﹤0.05)。LE、LE/HMG方案临床妊娠率高于CC、CC/HMG、HMG促排卵方案(P<0.05)。结论促排卵治疗增加IUI妊娠率,LE或LE/HMG方案促排卵IUI安全、有效,妊娠率高于其他促排卵方案。
作者 王冬梅 陈辉 曲緒琴 王惠 孙雪艳 张孝禹
机构地区 烟台市烟台山医院
出处 《山东医药》 CAS 2013年第38期57-60,共4页 Shandong Medical Journal
关键词 氯米芬 来曲唑 促排卵 夫精宫腔内人工授精 妊娠结局
分类号 R711.6 [医药卫生—妇产科学]
  • 相关文献

参考文献12

  • 1Verhulst SM, Cohlen BJ, Hughes E, et al. Intra-uterine insemina- tion for unexplained subfertility[ J ]. Cochrane Database Syst Rev, 2006,18(9) :38.
  • 2耿蔷,全松,郭遂群,邢福祺.来曲唑等4种促排卵药物用于宫腔内人工授精的疗效比较[J].实用妇产科杂志,2011,27(3):187-190. 被引量：29
  • 3Goverde A J, Lambalk CB, McDonnell J, et al. Further considera- tions on natural or mild hyperstimulatiou cycles for intrauterine in- semination treatment: effects on pregnancy and multip|e pregnancy rates[J]. Hum Reprod, 2005,20(11) :3141-3146.
  • 4刘金勇,王媁,刘嘉茵.自然周期和促排卵周期宫腔内人工授精临床结局的比较[J].实用妇产科杂志,2010,26(8):601-604. 被引量：41
  • 5Steures P, van der Steeg JW, Hompes PG, et al. Intrauterine in- semination with controlled ovarian hyperstimulation versus expect- ant management for couples with unexplained subfertility and an in- termediate prognosis: a randomised clinical trial [ J ]. Lancet, 2006,368 (9531) :216-221.
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二级参考文献17

  • 1Verhulst SM,Cohlen BJ.Intra-uterine insemination for unexplained subfertility[M] ,3th.the United States of America:JohnWiley Son8,2008:7-ll.
  • 2Bensdorp AJ,Cohlen BJ.Intra-uterine insemination for male subfertility[M].3th.the United States of America JohnWiley Sons,2008; 10-15.
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  • 5Steures P,Steeg JW,Hompes PG.Intrauterine insemination with controlled ovarian hyperstimulation versus expectant management for couples with unexplained infertility:collaborative effort on the clinical evaluation in reproductive medicine[J].Lancet,2006,3(68):216-221.
  • 6Bettio D,Venci A,Levi Setti PE.Chromosomal abnormalities in miscarriages after different assisted reproduction procedures[J].Placenta,2008,29 (1 B):126 -128.
  • 7Bensdorp AJ, Cohlen BJ, Heineman MJ, et al. Intrauterrine insemi- nation for male subfertility[ J]. Cochrane Database Syst Rev, 2007, 17 (4) :CD000360.
  • 8Holzer H, Casper R, Tulandi TA. A new era in ovulation induction [J]. Fertil Stefil,2006,85(2):277 -284.
  • 9Francavilla F, Seiarretta F, Sorgentone S, et al. Intrauterine insemi- nation with or without mild ovarian stimulation in couples with male subfertility due to oligo/astheno and/or teratozoospermia or antisperm antibodies : a prospective cross-over trial [ J ]. Fertil Steril, 2009, 92 (3) :1009 - 1011.
  • 10Bilu Y, Jinju L, Junzhao ZHAO, et al. Ovarian stimulation cycles combined with Intrauterine insemination for the treatment of infertility [J]. Fertil Steril, 2000,74(3) : 150-155.

共引文献62

同被引文献87

引证文献11

二级引证文献58

山东医药
2013年 第38期

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