期刊文献+

中西医结合治疗对急性分泌性中耳炎外周血T淋巴细胞亚群及免疫球蛋白水平的影响 被引量:13

Clinical efficacy of integrated Chinese and western medicine on acute secretory otitis media and its influence on peripheral blood T lymphocyte subgroup and immunoglobulin level
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摘要 目的探讨中西医结合在急性分泌性中耳炎治疗中的作用。方法急性分泌性中耳炎患者50例,共86个病耳,根据治疗方法不同分为治疗组和对照组,各25例,其中治疗组40耳,对照组46耳。对照组采用西医治疗,治疗组在西医治疗基础上应用中药方剂。观察患者治疗后的临床疗效,声阻抗检查病情恢复情况。流式细胞仪检测治疗前后T淋巴细胞亚群变化;速率比浊法检测血清IgG、IgA、IgM、补体C3、C4变化情况。结果治疗组临床有效率为95.0%,明显高于对照组有效率(78.3%)(P<0.05)。2组患者治疗前后T淋巴细胞亚群水平无显著变化(P>0.05)。与治疗前比较,治疗组治疗后血清IgA水平明显下降(P<0.05)。结论中西医结合治疗急性分泌性中耳炎临床效果明显,值得推广应用。 Objective To explore the role of integrated Chinese and western medicine on a- cute secretory otitis media (SOM). Methods Fifty patients with acute SOM (86 sick ears) were di- vided into treatment group (40 sick ears) and control group (46 sick ears) according to different therapeutic methods, 25 for each. The latter group was treated with western medicine and the for- mer was added with Chinese medicine. The clinical effects were compared in two groups, and recov- ery rate was determined by acoustic impedance after treatment. The changes of T lymphocyte sub- groups before and after treatment were detected with flow cytometer while serum IgG, IgA, IgM as well as alexin C3 and CA were determined by rate - nephelometry. Results Clinical effects of treat- ment group was 95.0 %, being evidently higher than control group (78.3 % ) ( P 〈 0.05). T lym- phocyte subgroup level in two groups showed no obvious difference (P 〉0.05), whereas serum IgA level decreased remarkably after treatment (P 〈 0.05). Conclusion Integrated Chinese and west- ern medicine has a significant effect on acute SOM, deserving to be widely promoted.
出处 《实用临床医药杂志》 CAS 2013年第19期44-46,共3页 Journal of Clinical Medicine in Practice
基金 中国高校医学期刊临床专项资金(11321115)
关键词 分泌性中耳炎 中西医结合 免疫 疗效 SOM integrated Chinese and western medicine immunity therapeutic ef-{eet
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