摘要
目的:探讨慢性扁桃体炎患者外周血T淋巴细胞亚群的特点及诊断意义。方法:选择40例慢性扁桃体炎患者和40例健康对照者,采用流式细胞技术对两组外周血T淋巴细胞亚群进行测定并比较两组间检测结果的差异。结果:慢性扁桃体炎组患者的CD4+及CD4+/CD8+比值明显低于健康对照组(P<0.01),CD8+与健康对照组相比差异无统计学意义(P>0.05);慢性扁桃体炎患者外周血CD4+ CD45RA+与Cystatin C浓度呈负相关(r=-0.276,P<0.05);CD3+、CD4+/CD8+与其ESR呈正相关(P<0.05)。结论:慢性扁桃体炎患者T细胞免疫功能失衡,CD4+ D45RA+T细胞亚群数值变化能预测慢性扁桃体炎患者肾损害。
Objective： To study the characteristics and diagnostic significance of detecting peripheral blood T lymphocyte subsets in patients with chronic tonsillitis.Methods： 40 cases patients with chronic tonsillitis patients and 40 cases of healthy control people were selected, and peripheral blood T lymphocyte subsets were detected with flow cytometric analysis, and difference were contrasted between chronic tonsillitis groups and healthy control groups. Results： CD4＋and CD4＋ / CD8＋ ratio was notable lower in chronic tonsillitis groups than in healthy control groups（P〈0.01）, CD8＋ was identical between chronic tonsillitis groups and in healthy control groups（P〉0.05）, CD4＋ and CD45RA＋ was negative correlative with Cystatin in peripheral blood （r=-0.276, P〈0.05）, CD3＋ and CD4VCD8＋ was positive correlative with ESR in peripheral blood（P〈0.05）.Conclusion： T cellular immunity was disbalance in patients with chronic tonsillitis, change of CD4＋ and CD45RA~ T could pretest kidney damage in patients with chronic tonsillitis.
出处
《中外医学研究》
2013年第5期48-49,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
