摘要
丝裂霉素C能够减轻组织粘连、纤维组织增生和瘢痕形成,因此被广泛应用于翼状胬肉手术以降低术后复发率.然而在取得一定疗效的同时丝裂霉素C还会引起多种严重并发症,并能延续到应用后相当长的时期,其治疗非常棘手.与自体结膜联合角膜缘干细胞移植相比,丝裂霉素C在降低翼状胬肉复发率上并无明显优势.所以,建议在翼状胬肉手术治疗中慎用或摒弃应用丝裂霉素C.
Mitomycin C （MMC）,as it could reduce tissue adhesions and scar formation,has been widely adopted in pterygium surgery to lower the recurrence rate.Upon a certain therapeutic effect obtained,a variety of ocular complications was combined and always occupies a quite long time after MMC application.once occurred,it was tough to cure.Compared to autologous limbal-conjunctival grafts,MMC has no apparent advantage to reduce reoccurrence of pterygium.Therefore,it is advised to abandon the use of MMC in pterygium surgery.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2013年第10期869-872,共4页
Chinese Journal of Ophthalmology
