摘要
目的观察并比较单纯翼状胬肉切除术及翼状胬肉切除联合角膜缘干细胞移植术治疗原发性翼状胬肉的临床疗效。方法回顾性系列病例研究。回顾性分析2011年8月至2012年5月在承德市中医院眼科门诊就诊的56例(61只眼)原发性翼状胬肉患者临床资料。其中男24例(26只眼),女32例(35只眼),随机分成两组。A组26例(28只眼)行单纯翼状胬肉切除术;B组30例(33只眼)行翼状胬肉切除联合角膜缘干细胞移植术。所有手术由同一术者操作。术后随访12个月,观察其复发率。两组间复发率差异比较采用χ2检验。结果 A组28只眼中复发6只眼,复发率21.4%。B组33只眼中复发2只眼,复发率6.0%。A组复发率显著高于B组(χ2=5.162,P<0.05)。两组术中及术后均未发生严重并发症。结论翼状胬肉切除联合角膜缘干细胞移植术是一种安全、有效的手术方式。
Objective To observe and compare the theraputic effects between simple pterygium excision and pterygium excision combined with limbus cornea stem cell transplantation in the treatment of primary pterygium. Methods This was a retrospective case series study. Sixty-one eyes in fifty-six patients with primary pterygium from Apr. 2011 to May. 2012 including 24 male(twenty-six eyes) and 32 female(thirty-five eyes) in Chengde traditional chinese medicine hospital were randomly divided into two groups.Group A(twenty-six patients,twenty-eight eyes) were undertaken simple pterygium resection while group B(thirty patients,thirty-three eyes) were carried excision of pterygium with limbus cornea stem cell transplantation surgery. All surgeries were performed by the same skilled surgeon. All patients were followedup after the operation for 12 months to investigate the recurrence rate. Chi-square test was used to evaluate the recurrence rate between these two groups. Results Group A: pterygium recurred in 6 eyes(21. 4%);Group B: pterygium recurred in 2 eyes(6%). The recurrence rate of group A was significantly higher than group B(χ2= 5. 162,P < 0. 05). No sever intraoperative and postoperative complications happened in two groups. Conclusion Pterygium excision combined with autoallergic limbus cornea stem cell transplantation is effective and safe in treating pterygium.
出处
《中华眼科医学杂志（电子版）》
2012年第2期27-29,共3页
Chinese Journal of Ophthalmologic Medicine(Electronic Edition)
关键词
翼状胬肉
手术
角膜缘干细胞
Pterygium
Surgery
Limbus cornea stem cell
