摘要
目的研究拐芹(Angelica polymorpha Maxim)地上部分的化学成分。方法采用硅胶柱色谱进行分离纯化,通过理化常数测定结合谱学分析鉴定化合物的结构。结果从拐芹中分离并鉴定了10个化合物,分别为二十五烷酸(Pentacosanoic acid)(Ⅰ),三十二烷酸(Lacceroicacid)(Ⅱ),α-香树脂醇(α-amyrenol)(Ⅲ),3-Hydroxy-3,6-dimethyl-2-(3-methylbut-2-enylidene)-3,3a,7,7a-tetrahydrobenzofuran-4(2H)-one(Ⅳ),拐芹色原酮A(Angeliticin A)(Ⅴ),去甲基丁香色原酮(Noreugenin)(Ⅵ),胡萝卜苷(Daucosterol)(Ⅶ),乙酰水合氧化前胡素(Oxypeucedanin hydrate acetate)(Ⅷ),蔗糖(Sucrose)(Ⅸ)和E-4-羟基-4-甲基-2戊烯酸(4-hydroxy-4-methyl-2-pentenoic acid)(Ⅹ)。结论化合物Ⅰ、Ⅱ、Ⅲ、Ⅷ、Ⅹ为首次从该植物中分离得到。
Objective To investigate the chemical composition of extraction from Angelica aerial parts of poly- morpha Maxim. Methods Silica gel column chromatography was employed for the isolation and purification. Re- sults Ten compounds Pentacosanoic acid （ 1 ）, Lacceroic acid （ 2 ）, Ⅲ-amyrenol （ 3 ）, 3-Hydroxy-3,6-dimethyl-2- （ 3- methylbut-2-enylidene）-3,3a, 7,7a-tetrahydrobenzofuran-4 （2H） -one （ 4 ）, Angeliticin A （ 5 ）, Noreugenin （ 6 ）, Dau- costerol （ 7 ）, Oxypeucedanin hydrate acetate （8）, Sucrose （ 9 ）, 4-hydroxy-4-methyl-2-pentenoic acid（10） were isolated and their structures elucidated by spectroscopic methods including 1H-NMR, 13C-NMR, IR and MS techniques. Conclusion Compounds 1,2,3,8,10 were isolated from A. polymorpha for the first time.
出处
《济宁医学院学报》
2013年第5期320-322,共3页
Journal of Jining Medical University
关键词
拐芹
化学成分
Angelica polymorpha Maxim
Aerial parts
Chemical composition
