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原发性颅内淋巴瘤的显微手术治疗及影响预后因素分析 被引量:1

Clinical efficacy of microsurgical treatment for primary intracranial lymphoma
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摘要 目的探讨原发性颅内淋巴瘤(PIL)显微手术治疗的效果,并分析影响患者预后的因素。方法对9例PIL进行显微手术切除,术后给予化疗,依据神经影像学结果,对残留肿瘤给予放疗、立体定向放射外科治疗。结果肿瘤全切2例,部分切除7例。出院后经7月~4.5年随访,部分切除的7例死亡,肿瘤全切2例存活。结论采用显微手术全切病变可改善预后,对不能全切者选择放疗或立体定向放射外科治疗是一重要方法,但多数患者预后不好。 Objective To explore the clinical efficacy of microsurgical treatment for primary intracranial lymphoma (PIL). Methods The clinical data of 9 patients with PIL, who underwent microsurgery from June 2003 to May 2012, were analyzed retrospectively. All patients received chemotherapy after operation and the patients with residual tumors also received radiotherapy or stereotactic radiosurgery. Results Total resection of the tumors was obtained in 2 patients and subtotal in 7. All patients were followed up from 7 months to 4.5 years with a mean time of 1.3 years, and the outcomes showed that 7 patients with subtotal resection of the tumors died and 2 patients with total resection of the tumors survived. Conclusions Total resection of the tumors helps to improve the pronoses of patients with PIL. The chemotherapy, stereotactic radiosuegery and radiotherapy are very important for patients with residual tumors. However, the prognoses of most patients with PIL are poor.
出处 《中国临床神经外科杂志》 2013年第9期519-521,共3页 Chinese Journal of Clinical Neurosurgery
关键词 原发性颅内淋巴瘤 显微手术 效果 Primary intracranial lymphoma Microsurgery Prognosis
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