摘要
目的观察直肠癌化疗患者医院感染发生的危险因素,分析其在不同临床特征中感染率的差异,以期为临床工作提供理论帮助。方法对医院630例直肠癌化疗患者的危险因素和临床特征进行分析研究。结果共121例患者发生医院感染,医院感染率为19.21%,其中呼吸道83例占68.60%,泌尿系7例占5.79%,胃肠道5例占4.12%,造瘘口21例占17.36%,皮肤3例占2.48%,血液2例占1.65%;医院感染的发生与性别、年龄、住院时间、手术、白细胞计数、侵入性操作、抗菌药物的使用密切相关(P<0.05)。结论直肠癌化疗患者应重点监测,加强重点患者的风险监测,同时进行有效的干预措施,对减少直肠癌化疗医院感染的发生有重要价值。
OBJECTIVE To observe the risk factors of nosocomial infections in the rectal carcinoma patients undergoing chemotherapy and analyze the infections rate of the patients with different clinical features so as to guide theclinical treatment. METHODS The risk factors for the nosocomial infections in 630 rectal cancer patients undergo-ing chemotherapy were analyzed, and the clinical features were observed. RESULTS The nosocomial infections oc-curred in 121 cases of patients with the incidence rate of 19. 21 %,including 83 （68. 60%） cases with respiratorytract infections,7（5. 79%） cases with urinary tract infections,5 （4. 12%） cases with gastrointestinal tract infections ,21（17. 36%） cases with fistula infections, 3 （2. 48%） cases with skin infections, and 2 （1. 65%） caseswith blood infections. The incidence of the nosocomial infections was closely related to the gender, age,hospitalization duration,surgery, leukocyte count, invasive operation,or use of antibiotics （P〈0. 05）. CONCLUSION It isnecessary to focus on the monitoring of the patients undergoing chemotherapy, strengthen the risk surveillance,and take effective interventions so as to reduce the incidence of nosocomial infections in the rectal carcinoma pa-tients undergoing chemotherapy.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第17期4146-4147,共2页
Chinese Journal of Nosocomiology
关键词
直肠癌
化疗
医院感染
危险因素
Rectal carcinoma
Chemotherapy
Nosocomial infection
Risk factor
