摘要
目的观察氟比洛芬酯切皮前给药对腹腔镜子宫切除手术患者术中应激反应的影响。方法选择40例全麻下行腹腔镜子宫切除手术患者,ASA分级Ⅰ～Ⅱ级,随机分为两组(n=20):对照组(Ⅰ组)采用异丙酚、瑞芬太尼静脉复合全麻,研究组(Ⅱ组)在异丙酚、瑞芬太尼静脉复合全麻的基础上,于术前10 min静注氟比洛芬酯50 mg。观察两组患者术中血流动力学变化;测定入室后、插管后、切皮后10 min和拔管后血糖和皮质醇的变化。结果研究组术中MAP、HR均比对照组降低(P﹤0.05),术中皮质醇测定对照组高于研究组(P﹤0.05)。术后对照组血糖高于研究组(P﹤0.01)。结论氟比洛芬酯超前镇痛可减轻患者术中应激反应。
Objective To observe the effect of flurbiprofen to stress response during operation for laparoscopic hysterectomy patients. Methods Selected 40 laparoscopic hysterectomy patients, ASA classification I - II ,randomLy divided into two groups（n=20）, control group（ I ） with propofol and remifentanil vein complex anesthesia, research group （ II ） on the basis of control group,patients injected flurbiprofen 50mg before operation 10min. Observed two groups＇ haemodynamic changes and extubation time during operation, and measure changes of the plasma Cor and plasma glucose after patients enter operation room, intubation, cutting the skin lOmin and extubation. Results MAP, HR during operation of all research group patients was lower than control group （P 〈 0.05）, cortisol measurement during operation of control group was higher than research group（P 〈 0.05）. Blood sugar of control group after operation was higher than research group（P 〈 0.01 ）. Conclusion Flurbiprofen preemptive analgesia can reduce stress response during operation.
出处
《中国现代医生》
2013年第28期88-89,95,共3页
China Modern Doctor
关键词
氟比洛芬酯
超前镇痛
应激反应
手术
腹腔镜子宫切除术
Flurbiprofen
Preemptive analgesia
Stress response
Operation
Laparoscopic hysterectomy
