摘要
目的:探讨氟比洛芬酯超前镇痛用于小儿前臂骨折手术的镇痛效果及安全性。方法:将60例择期行前臂骨折切复内固定术的患儿分为A、B、C组,每组各20例。3组均行相同的麻醉诱导及术中麻醉,在此基础上,A组、B组分别于手术前、手术结束后缓慢静注1mg/kg(生理盐水稀释至5ml)氟比洛芬酯,C组手术前缓慢静注生理盐水5ml。观察术后10h内疼痛评分,恶心、呕吐等不良反应。结果:3组患儿术后恶心、呕吐的发病率均无显著性差异(均P>0.05),凝血功能均无异常。3组患儿术后2h、4h、8h、10h疼痛评分情况,C组均显著高于B组(均P<0.05),B组均显著高于A组(均P<0.05)。结论:氟比洛芬酯超前镇痛较术后应用更能减轻小儿前臂手术患儿术后急性疼痛,且无明显不良反应。
Objective：To investigate the safety and effectiveness of analgesia used by flurbinprofen axetil before operation in pediatric forearm fracture patients.Methods：Sixty children at American Society of Anesthesiologists（ASA）physical state Ⅰ aged 4 years to 8 years were randomly divided into 3 groups.Group A（n=20）undergoing vein administration of flurbinprofen axetil 1mg/kg before operation,group B undergoing vein administration of flurbinprofen axetil 1mg/kg after operation,group C undergoing vein administration of 5ml 0.9% sodium choride.The pain scoring was conducted until 10 hours after thr operation.Results：The adverse reactions were not significantly different among the groups.The pain scales were significantly lower in children received flurbinprofen axetil before operation（Group A）than others（all P0.05）.Conclusion：The preemptive analgesic can reduce postoperative pain.
出处
《中日友好医院学报》
2012年第2期90-92,共3页
Journal of China-Japan Friendship Hospital
关键词
氟比洛芬酯
超前镇痛
前臂骨折手术
儿童
flurbinprofen axetil
preemptive analgesic
arm surgery
children
