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白细胞介素-17受体C

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摘要 白细胞介素-17受体C(interleukin-17 receptor C,IL-17RC)是新发现的IL-17家族受体,组织分布广泛,如分布于大多数血管、淋巴管的内皮细胞、鳞状上皮等。IL-17RC是IL-17F的受体,也可以与IL-17A以及IL-17A、IL-17F组成的复合物结合。此外,IL-17RC还可与IL-17RA组成受体复合物后再与相应的配体结合,从而激活细胞内的信号转导系统。
作者 尤青海 牛成成 孙耕耘
机构地区 安徽医科大学第一附属医院呼吸内科 安徽医科大学第一附属医院成人输液厅
出处 《生理科学进展》 CAS CSCD 北大核心 2013年第4期301-304,共4页 Progress in Physiological Sciences
基金 国家自然科学基金(81100053 81070054)资助课题
关键词 白细胞介素 受体 信号转导
分类号 R392 [医药卫生—免疫学] R593 [医药卫生—内科学]
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参考文献11

  • 1Kuestner RE, Taft OW, Haran A, et al. Identification of the TL-17 receptor related molecule IL-l7RC as the receptor for IL-17F. J Immunol, 2007,179: 5462 -5473.
  • 2Haudenschild DR, Curtiss SB, Moseley TA, et al. Genera?tion of interleukin-l7 receptor-like protein (IL-17RL) in prostate by alternative splicing of RNA. Prostate, 2006, 66 : 1268 - 1274.
  • 3Ho AW, Gaffen SL. IL-l7RC: a partner in IL-17 signaling and beyond. Semin lmmunopathol. 2010,32 : 33 - 42.
  • 4Fujie H, Niu K, Ohba M, et al. A distinct regulatory role of Thl7 cytokines IL-l7 A and IL-l7 F in chemokine secretion from lung microvascular endothelial cells. Inflammation. 2012,35 : [lt9 - 1t3!.
  • 5Valente AJ, Yoshida T, Gardner JO. et al. Interleukin-17 A stimulates cardiac fibroblast proliferation and migration via negative regulation of the dual-specificity phosphatase MKP- 1I0USP-l. Cell Signal, 2012,24 : 560 -568.
  • 6Hirai Y,Iyoda M,Shibata T,et al. IL-17A stimulates granu?locyte colony-stimulating factor production via ERKlI2 but not p38 or JNK in human renal proximal tubular epithelial cells. Am J Physiol Renal Physiol,2012,302 : F244 - F250.
  • 7Liu L,Ge O,Ma L,et al. Interleukin-17 and prostaglandin E2 are involved in formation of an M2 macrophage-dominant mi?croenvironment in lung cancer. J Thorac Oncol, 2012, 7 : [091 - llOO.
  • 8Liu Y, Zhu H, Su Z, et al. IL-17 contributes to cardiac fi?brosis following experimental autoimmune myocarditis by a PKCfYErkll2/NF -KB-dependent signaling pathway. lnt Im?munol, 2012,24 : 605 -612.
  • 9Kudo M, Melton AC, Chen C, et al. IL-17 A produced by ex/3 T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contrac?tion. Nat Med, 2012,18: 547 -554.
  • 10尤青海,张丹,孙耕耘,岳扬,王楠.肿瘤坏死因子α对大鼠肺微血管内皮细胞表达白细胞介素17受体C的影响[J].中华医学杂志,2013,93(2):138-141. 被引量：4

二级参考文献11

  • 1Kuestner RE, Taft DW, Haran A, et al. Identification of the IL- 17 receptor related molecule IL-17RC as the receptor for IL-17F. J Immunol, 2007, 179 : 5462-5473.
  • 2You QI-I, Sun GY, Wang N, et al. Interleukin-17F-induced pulmonary microvascular endothelial monolayer hyperpermeability via the protein kinase C pathway. J Surg Res, 2010, 162: 110- 121.
  • 3Mong PY, Petmlio C, Kaufman HL, et al. Activation of Rho kinase by TNF-ais required for JNK activation in human pulmonary micmvascular endothelial cells. J Immunol, 2008, 180: 550-558.
  • 4Shah NG, Tulapurkar ME, Damarla M, et al. Febrile-range hyperthermia augments reversible TNF-ot-induced hyperpermeahility in human microvascular lung endothelial cells. Int J Hyperthermia,2012, 28 : 627-635.
  • 5Ho AW, Shen F, Conti HR, et al. IL-17RC is required for immune signaling via an extended SEF/IL-R signaling domain in the cytoplasmic tail. J Immunol, 2010, 185: 1063-1070.
  • 6Roussel L, Houle F, Chan C, et al. IL-17 promotes p38 MAPK- dependent endothelial aetivation enhancing neutrophil recruitment to sites of inflammation. J Immunol, 2010, 184: 4531-4537.
  • 7Fujie H, Niu K, Ohba M, et al. A distinct regulatory role of Thl7 cytokines IL-17A and IL-17F in chemokine secretion from lung microvascular endothelial cells. Inflammation, 2012, 35 : 1119- 1131.
  • 8Sun SX, Ge BX, Miao CH. Effects of preconditioning with sevoflurane on TNF-ct-induced permeability and activation of p38 MAPK in rat pulmonary microvascular endothelial cells. Cell Biochem Biophys, 2011,61: 123-129.
  • 9Tang HF, Lu JJ, Tang JF, et al. Action of a Novel PDFA inhibitor ZL-n-91 on lipopolysaccharide-induced acute lung injury. Int Immunopharmacol, 2010, 10: 406-411.
  • 10Numasaki M, Takahashi H, Tomioka Y, et al. Regulatory roles of IL-17 and IL-17F in G-CSF production by lung microvascular endothelial cells stimulated with IL-1β and/or TNF-α. Immunol Lett, 2004, 95: 97-104.

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生理科学进展
2013年 第4期

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