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白细胞介素-1家族受体 信号转导及与疾病的关系 被引量:3

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摘要 白细胞介素(interleukin,IL)1是细胞因子网络中的一种重要因子,在固有免疫和获得性免疫反应中发挥着重要作用。IL-1存在于体内各组织中,具有广泛的生物学活性。目前研究IL-1的家族成员有11种,尽管有些成员的作用机制还不是很清楚,但它们在生物调节和临床疾病等方面所发挥的作用越来越受到重视。国内外对它们的研究主要包括它们的受体、信号转导通路、功能以及与临床疾病的关系等。本文就国内外对IL-1家族的研究做一综述。
出处 《济宁医学院学报》 2012年第6期434-436,439,共4页 Journal of Jining Medical University
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