同型半胱氨酸在2型糖尿病肾病中的诊断价值被引量：1

Diagnostic value of homocysteine in type 2 diabetic nephropathy

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摘要目的:观察血浆同型半胱氨酸在糖尿病肾病中的诊断价值。方法:测定单纯糖尿病组,早期糖尿病肾病组和临床糖尿病肾病组各组尿蛋白排泄率(UAER)、血浆同型半胱氨酸(t-Hcy),以及其他危险因素资料。结果:早期糖尿病肾病组t-Hcy测定明显高于单纯糖尿病组,临床糖尿病肾病与早期糖尿病肾病比较,t-Hcy升高,差异均有统计学意义(P<0.05);t-Hcy测定与年龄、病程、HbA1C、LDL、BUN、Cr、UAER正相关。ROC曲线下面积分析,t-Hcy测定具有糖尿病肾病诊断价值。结论:t-Hcy是糖尿病肾病诊断的敏感指标。 Objective To observe the diagnostic value of plasma homocysteine in diabetic nephropathy. Method UAER and t- Hcy was measured in diabetic group,early diabetic nephropathy and clinical diabetic nephropathy group, as well as other risk factors informa- tion. Results The t - Hey of early diabetic nephropathy group was significantly higher than the diabetic group, the t - Hey of clinical diabet- ic nephropathy was significantly higher compared with the early diabetic nephropathy group. The t - Hcy level positively correlated with age, disease duration, HbA1 C, LDL, BUN, Cr and UAER. By the area under the ROC curve analysis, t- Hcy determination can be used for the diagnosis of diabetic nephropathy. Conclusion The t -Hcy is a sensitive indicator of the diagnosis of diabetic nephropathy.

作者王荣贾爱华刘昕艳

机构地区陕西省榆林市第一医院内分泌科

出处《吉林医学》 CAS 2013年第25期5102-5103,共2页 Jilin Medical Journal

关键词血浆同型半胱氨酸尿微量白蛋白排泄率糖尿病肾病 Homocysteine Urinary albumin excretion rate Diabetic nephropathy

分类号 R587.2 [医药卫生—内分泌]

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