摘要
目的探讨2型糖尿病肾病患者同型半胱氨酸和C反应蛋白水平变化情况。方法采用回顾性分析我院收治2型糖尿病。肾病患者临床资料,观察其同型半胱氨酸和c反应蛋白水平情况。结果糖尿病肾病组血糖、24h蛋白尿、同型半胱氨酸、CRP含量均高于对照组,同时同型半胱氨酸水平〉15μmol/L患者CRP含量明显高于同型半胱氨酸水平≤15μmol/L组,P〈0.05,差异均有统计学意义。结论同型半胱氨酸和C反应蛋白升高可能是糖尿病肾病发病的危险因素,对于糖尿病肾病患者进行同型半胱氨酸和C反应蛋白水平监测具有重要的临床意义。
Objective To investigate the type 2 diabetic nephropathy in patients with homocysteine and C-reactive protein levels. Methods A retrospective analysis of our hospital clinical data of patients with type 2 diabetic nephropathy, observed homocysteine and C-reactive protein levels. The results of diabetic nephropathy blood glucose, 24h proteinuria, homoeysteine, CRP levels were higher homocysteine levels〉 15 ≤mol / L in patients with CRP levels significantly higher than the levels of homocysteine ≤ 15 ≤mol / L group, P 〈0.05, differences were statistically significant. The conclusions of homocysteine and C-reactive protein levels may be risk factors for dia- betic nephropathy, homecysteine and C-reactive protein levels in monitoring patients with diabetic nephropathy has important clinical significance.