摘要
目的探讨心脏再同步化治疗(CRT)难治性心力衰竭的效果。方法随机选择2009年6月至2012年1月在北京军区总医院住院治疗的61例因药物治疗不理想的高血压心力衰竭患者,超声心动图检测证实存在明显的室间、伴/不伴室内机械性不同步。将所有患者分成两组:药物治疗组32例,CRT治疗组29例。CRT组患者通过超声评估选择起搏器电极植入位置,并在超声指导下优化起搏参数。比较两组患者6个月后及CRT组治疗前后临床及超声指标间的差异。结果 CRT组患者术后6个月临床症状明显改善,心脏同步性、6分钟步行距离(6MWD)、左心室射血分数(LVEF)、左心室舒张末内径(LVDd)与本组术前及药物治疗组6个月后比较,均有统计学意义(P<0.05)。结论 CRT治疗对难治性心力衰竭具有显著的疗效。
Objective To explore the effect of cardiac resynchronization therapy（CRT） on refractory heart failure（RHF） in the patients with hypertension.Methods From June 2009 to January 2012,61 hypertensive patients with heart failure admitted by General Hospital of Beijing Military Command with no satisfactory medication treatment effect were randomly selected.There were desynchronization between the two ventriculars with / without intraventricular desynchronization.The patients were divided into two groups.One group of 32 cases continued taking medicine,the other group of 29 cases received CRT.Pacemaker implant position was selected by untrasonography and pacing parameters were optimized under ultrasound guidance.6 months later,all clinical data were analysed and compared.Results The index such as 6 minutes walking distance（6MWD）,left atrial distance（LAD）,left ventricular ejection fraction（LVEF）,and left ventricular diastolic distance（LVDd） were all better in the group of CRT compared with before treatment and the medication group（P 0.05）.Conclusion The outcome of RHF treated by CRT can be improved significantly.
出处
《医学综述》
2013年第16期3045-3046,共2页
Medical Recapitulate
关键词
心脏再同步化治疗
难治性心力衰竭
6分钟步行距离
Cardiac resynchronization therapy
Refractory heart failure（RHF）
6 minutes walking distance
