摘要
目的：观察右房双室起搏治疗慢性心力衰竭的近期疗效。方法：选择NYHAⅢ级~Ⅳ级、LVEF≤35%、QRS时限≥120 m s、窦性心律的CHF患者30例,成功植入三腔起搏器后,以起搏器植入术前及术后1月的6 m in步行距离、MQOL、QRS波时限、LVEDD、LVEF、TPSD、NT-proBNP为评价指标,观察右房双室起搏治疗CHF的近期疗效。结果：右房双室起搏治疗1月后,患者的各疗效评价指标均得到明显改善（P〈0.05）。6 m in步行距离由（267±34）m提高至（318±37）m;MQOL由（30±7）下降至（19±8）;QRS波时限由（171±22）m s缩短至（130±8）m s;LVEF由（29±5）%提高至（37±6）%;LVEDD由（78±6）mm减小至（67±8）mm;TPSD由（108±29）m s下降至（59±7）m s;NT-proBNP由（3 286±1 702）pg/m l下降至（1 871±901）pg/m l。结论：右房双室起搏治疗窦性心律、完全性左束支传导阻滞的慢性心力衰竭患者的疗效确切。
Objective： To observe the short-term curative effect of the right atrium and biventricular pacing in patients with chronic heart failure.Methods： Thirty patients who had LVEF less than or equal to 35%,a QRS duration greater than or equal to 0.12 seconds,sinus rhythm and NYHA function Class Ⅲ or ambulatory Class Ⅳ heart failure symptoms with optimal medical therapy were collected after the successful implantation of CRT/CRTD.Took 6-minute walk distance,Minnesota quality-of-life score（MQOL）,QRS duration in surface electrocardiogram,left ventricular end-diastolic dimension（LVEDD）,LVEF,the difference between systolic time to peak from left interventricular septum to the basal segment of lateral wall（TPSD） and NT-proBNP as the efficacy evaluation indexes on the day before the implantation of CRT/CRTD and the first month after that,to observe the short-term curative effect of the the right atrium and biventricular pacing in patients with chronic heart failure.Results： After the right atrium and biventricular pacing for one month,the seven efficacy evaluation indexes were significantly improved（P0.05）.The 6-minute walk distance was increased from（267±34） m to（318±37） m.The MQOL was decreased from（30±7） to（19±8）.The QRS duration was shortened from（171±22） ms to（130±8） ms.The LVEDD was reduced from（78±6） mm to（67±8） mm.The LVEF was improved from（29±5）% to（37±6）%.The TPSD dropped from（108±29） ms to（59±7） ms.The NT-proBNP was lowered from（3 286±1 702） pg/ml to（1 871±901） pg/ml.Conclusion： The curative effect of the the right atrium and biventricular pacing is definite.In patients with severe congestive heart failure,sinus rhythm,and left bundle-branch block.
出处
《河南医学研究》
CAS
2011年第2期176-178,共3页
Henan Medical Research
关键词
心血管病学
心力衰竭
再同步化治疗
cardiology
heart failure
cardiac resynchronization therapy
