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同型半胱氨酸在糖尿病肾病中的作用 被引量：6

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摘要 糖尿病可引起多种并发症，如视网膜病变、周围神经病变、糖尿病。肾病（DN）等。DN是临床常见和多发的糖尿病并发症，是糖尿病最严重的全身性微血管病变之表现。DN时肾小球肥大，基底膜增厚，细胞外基质积聚，导致弥漫性或结节性肾小球硬化和肾功能衰竭。研究证明，
作者 刘玮琳 孙星 李素琴
机构地区 河北省老年病医院 河北医科大学第一医院 河北省疾病预防控制中心
出处 《河北医药》 CAS 2013年第17期2635-2636,共2页 Hebei Medical Journal
关键词 糖尿病肾病 同型半胱氨酸
分类号 R587.24 [医药卫生—内分泌]
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参考文献8

  • 1Dronavalli S, Duka I, Bakris GL. The pathogenesis of diabetic nephropa- thy. J Nat Clin Pract Endocrinol. Metab ,2008,4:444-452.
  • 2Clarke R, Daly L, Robinson K, et al. Hyperhomocysteinemia: an inde- pendent risk facter for vasculer disease. N Engl J Med, 1991,324:1149- 1155.
  • 3刘鹏,王德宝,张凤梅,陈颖颖.替米沙坦对早期糖尿病肾病患者血浆同型半胱氨酸及颈动脉内膜中层厚度的影响[J].中国全科医学,2012,15(21):2431-2433. 被引量：24
  • 4Hlavodec J, Sommemva Z, Pisarikova A, et al. Homeeysteinemia and en- dothelial damage after nelhionine load. Thrcmb Res, 1997,88:361-364.
  • 5Souissi M, Feki M, Mourali S, et al. Homocysteinemia and coronaryartery disease;a case - control stuty in a Tunisian population. Arch Mal Coeur Vaiss ,2006,99:781-785.
  • 6陆明,陈卫东.高同型半胱氨酸血症与糖尿病肾病相关性研究进展[J].蚌埠医学院学报,2009,34(3):272-275. 被引量：25
  • 7Souissi M, Feki M, Mourali S, et al. Homocysteinemia and coronary artery disease;a case-control stuty in a Tunisian population. Arch Mal Coeur- Vaiss ,2006,99:781-785.
  • 8Suliman ME, Stenvinkel P, Heimburger O, et al. Plasma sulfur amino acids in relation to cardiovascular disease, nutritional status, and diabetes mellitus in patients with chronic renal failure at start of dialysis therapy. Am J Kidney Dis,2002 ,40 :480-488.

二级参考文献41

  • 1李剑波,成玉泽,戴庆,张瑜,王艳娟,陈继文,石敏.血浆同型半胱氨酸水平对于2型糖尿病早期肾病的独立预测意义[J].中华临床医师杂志（电子版）,2010,4(5):574-577. 被引量：23
  • 2Fallon UB, Virtamo J, Young I, et al. Homocysteine and Cerebral Infarction in Finnish Male Smokers [ J ]. Stroke, 2003,34 ( 6 ) :1359 -1363.
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  • 5Suliman ME, Stenvinkel P, Heimbiirger O, et al. Plasma sulfur amino acids in relation to cardiovascular disease, nutritional status,and diabetes mellitus in patients with chronic renal failure at start of dialysis therapy [ J ]. Am J Kidney Dis, 2002,40 ( 3 ) : 480 - 488.
  • 6Chambers JC, Ueland PM, Wright M, et al. Investigation of relationship between reduced, oxidized, and protein-bound homocysteine and vascular endothelial function in healthy human subjects[ J]. Circ Res,2001,89 ( 2 ) : 187 - 192.
  • 7Pavia C, Ferrer I, Vails C, et al. Total homocysteine in patients with type 1 diabetes [ J ]. Diabetes Care, 2000,23 ( 1 ) : 84 - 87.
  • 8Gillum R. Distribution of serum total homocysteine and its association with diabetes and cardiovascular risk factors of the insulin resistance syndrome in Mexican American men:the Third National Health and Nutrition Examination Survey [ J]. Nutr J, 2003,2(8) :6.
  • 9Duncan GE, Li SM, Zhou XH. Age and kidney function are the primary correlates of fasting plasma total homocysteine levels in non-diabetic and diabetic adults. Results from the 1999 - 2002 National Health and Nutrition Examination Survey [ J ]. Nutr Metab (Lond) ,2005,2(5) :13.
  • 10Sandhu JS, Singh I, Aggarwal SP, et al. Plasma homocysteine and insulin in diabetic nephropathy: relationship to body mass index [J]. Ren Fail,2004,26(6) :689 -693.

共引文献47

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二级引证文献42

河北医药
2013年 第17期

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