摘要
目的：分析孕中期产前筛查在降低新生儿缺陷发生率方面的意义。方法：对来我院进行孕前检查的怀孕时间为15周~20周的孕妇临床资料进行分析。使用时间分辨法,并用free-β-HCG,血清AFP作为检查的指标,对孕妇实施血清学产前筛查,最后风险值的计算则选用Risk2T软件。并对13/18三体高危孕妇实施羊水穿刺产前诊断。结果：本研究中的1 000例孕妇,在经过筛选后发现唐氏综合征高危孕妇的有100例,低危孕妇120例。50例13/18三体高危孕妇,23例开放性神经管缺陷高危孕妇。结论：有效的孕中期产前筛查能够在一定程度上减少新生儿缺陷的发生率。
Objective： Analyse the meamings of the second trimester prenatal screening in reducing the incidence of birth defects.Methods： Analyze the clinical data of pregnant women with the time of pregnancy 15 weeks to 20 weeks who come to our hospital for pre-pregnancy check.Use time resolution method,as well as free-β-HCG,serum AFP as check index.Pregnant women implementation serology prenatal screening,and finally choose Risk2T software to calculate the value-at-risk.And we implement amniotic fluid puncture prenatal diagnosis on13/18 three body high-risk pregnant women.Results：Our study has 1 000 cases of pregnant women,after screening we found 100 cases of pregnant women with high-risk down’s syndrome,120 cases of pregnant women with low-risk down’s syndrome,50 cases of pregnant women with 13/18 three body high-risk,23 cases of pregnant women with high-risk open neural tube defect.Conclusion：The effective second trimester prenatal screening can reduce the incidence of birth defects in some cases.
出处
《中国医药导刊》
2013年第5期766-767,共2页
Chinese Journal of Medicinal Guide
关键词
孕中期产前筛查
新生儿缺陷
唐氏综合征
开放性神经管缺陷
高危孕妇
Second trimester prenatal screening
Birth defects
Down syndrome
Open neural tube defects
Risk pregnant women
