摘要
目的 :了解 2型糖尿病高危人群空腹血糖分布规律及其对糖尿病的筛检价值。方法 :对无糖尿病症状的6 80例 2型糖尿病高危人群行 75 g口服葡萄糖耐量试验 ,对其空腹血糖水平分组分析 ,并评价不同水平空腹血糖对糖尿病的筛检价值。结果 :糖尿病、糖耐量低减和糖耐量正常的发生率分别为 19.85 %、2 0 .14%和 6 0 .0 0 % ;空腹血糖均值分别为 ( 6 .30± 0 .93) mm ol/ L、( 5 .2 5± 0 .83 ) mm ol/ L和 ( 4.5 6± 0 .74) mm ol/ L ( P值均 <0 .0 5 ) ;空腹血糖95 %的可信区间分别为 6 .10～ 6 .6 5 m mol/ L ,5 .2 0～ 5 .5 5 m mol/ L和 4.6 1～ 4.88m mol/ L。评价筛检试验显示在糖尿病高危人群中各指标在空腹血糖≥ 6 .0 m mol/ L或≥ 6 .5 mmol/ L时对糖尿病的综合预测价值略优于空腹血糖≥ 7.0 mmol/ L。结论 :在高危人群中筛检糖尿病效能较高 ,空腹血糖仍不失为发现糖尿病的早期简便方法 。
Objective:To investigate the distribution of fasting blood glucose(FBG) in high risk population of type 2 diabetes mellitus(DM) and to assess the screening efficiency of FBG.Methods:75 g oral glucose tolerance test (OGTT) was used in 680 cases with hypertension,hyperlipidemia,obesity,coronary heart disease and family history of DM.Results:According to the diagnositc criterion of DM,the ratio of impaired glucose tolerance(IGT) and normal glucose tolerance(NGT) were 19 84% and 20 14% respectively.The prevalent rate was 60 00%.The average levels of FBG in DM,IGT and NGT were (6 30±0 93) mmol/L,(5 25±0 83)mmol/L and (4 56±0 74)mmol/L respectively;and 95% confidence intervals of FBG were 6 10～6 65 mmol/L,5 20～5 55 mmol/L and 4 61～4 88 mmol/L with significant differences between these three groups ( P <0 05 respectively).The screening evaluation showed that both sensitivity and specificity at FBG≥6 0 mmol/L or FBG≥6 5 mmol/L were better than that at FBG≥7 0 mmol/L.Conclusion:This study suggested that FBG be a higher efficient test in screening DM and IGT in high risk groups and it also be an ideal methold for diagnosing DM and IGT.
出处
《中国慢性病预防与控制》
CAS
2000年第5期216-218,共3页
Chinese Journal of Prevention and Control of Chronic Diseases
关键词
糖尿病
糖耐量低减
空腹血糖
流行病学
Diabetes mellitus
Impaired glucose tolerance
Fasting blood glucose
OGTT
