摘要
目的分析急性冠状动脉综合征患者血超敏c反应蛋白（hs—CRP）、同型半胱氨酸（Hey）、可溶性CD40配体（sCD40L）与冠状动脉狭窄程度的相关性。方法110例急性冠状动脉综合征患者作为观察组，60例稳定型心绞痛患者作为对照组，测定患者血hs—CRP、Hey及sCD40L，急性冠状动脉综合征患者行冠状动脉造影判断狭窄的程度。结果观察组患者血hs—CRP、Hey、sCD40L均比对照组明显升高，两组比较差异有统计学意义（P〈0．01）。观察组患者冠状动脉狭窄程度评分为（95．9±10．9）分，与hs—CRP呈正相关（r=0．2166，P〈0．05），与Hey呈正相关（r=0．2454，P〈0．05），与sCD40L呈正相关（r=0．5186，P〈0．05）。结论检测急性冠状动脉综合征患者血hs—CRP、Hcy、sCD40L可以反映冠状动脉的狭窄程度。
Objective To study the relationship between high-sensitivity C-reactive protein （hs- CRP）, homocysteine（ Hcy）, soluble CD40 ligand （sCD40L） and the degree of coronary stenosis in pa- tients with acute coronary syndrome. Methods One hundred and ten patients with acute coronary syn- drome were enrolled into the observation group and 60 patients with stable angina were enrolled into the control group. The hs-CRP, Hcy and sCD40L were detected. The degree of coronary stenosis of acute coronary patients were determined by coronary angiography. Results The hs-CRP, Hcy and sCD40L in the observation group were higher than those in the control group. There was a significant difference be- tween the two groups（ P 〈0. 01 ）. Coronary stenosis score in the observation group was 95.9 ± 10. 9, which had a significantly positive with hs-CRP（ r = 0. 2166,P 〈0. 05）, Hcy（ r =0. 2454, P 〈0. 05） and sCD40L（ r = 0. 5186,P 〈0.05）. Conclusions Detection of serum hs-CRP, Hcy, sCD40L of a- cute coronary syndrome can reflect coronary stenosis.
出处
《中国实用医刊》
2013年第15期44-46,共3页
Chinese Journal of Practical Medicine
