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2001~2010年中国先天性马蹄内翻足的流行病学分析 被引量:17

An Descriptive Epidemiological Study on Congenital Clubfoot in China during 2001 to 2010
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摘要 目的对全国先天性马蹄内翻足资料进行流行病学分析,了解我国先天性马蹄内翻足的变化趋势和影响因素。方法收集中国出生缺陷监测网2001~2010年监测的孕28周至产后7d住院分娩的围产儿资料,包括活产、死胎和死产,进行流行病学分析。结果 2001~2010年共监测8 273 382例围产儿,其中先天性马蹄内翻足4 233例,全国的先天性马蹄内翻足发生率为5.12/104,十年期间没有明显的变化趋势(χ2=2.43,P>0.05)。城市发生率为4.90/104,农村发生率为5.43/104;男性发生率为5.31/104,女性发生率为4.73/104;西部发生率为7.00/104,中部发生率为4.52/104,东部发生率为4.27/104;南方发生率为5.82/104,北方发生率为4.34/104,差异均有统计学意义(P<0.05)。男女间先天性马蹄内翻足的受累部位分布没有差异(χ2=1.74,P>0.05)。结论 2001~2010年我国先天性马蹄内翻足发生率没有明显的变化趋势,发生率存在城乡、地区差异和性别差异。我国先天性马蹄内翻足发生率低于国外报道。 Objective To understand the trend of prevalence of congenital clubfoot and its epidemiological eharacterisitics in China during 2001 to 2010. Methods The data of the perinatal children with congenital clubfoot from 2001 to 2010 in the birth defects monitoring program were collected and analyzed, and the perinatal children were defined from the pregnancy of 28 weeks to postnatal 7 days, including live births, fetal deaths and stillbirths. SPSS16.0 software was used to analyze the data. Results A total of 4 233 cases were identified with congenital clubfoot among 8 273 382 births, with a prevalence of 5.12/104. There was no increasing trend or decreasing trend on the prevalence of congenital clubfoot to be found in China during 2001 to 2010 (χ2=2.43,P〉0. 05). The prevalence of congenital clubfoot in urban and rural areas was 4.90 and 5.43 per 10 000 births respectively. The prevalence of congenital clubfoot in male and female babies was 5.31 and 4.73 per 10 000 births respectively. The prevalence of congenital clubfoot in west, middle and east region was 7. 00, 4. 52 and 4. 27 per 10 000 births respectively. The prevalence of congenital clubfoot in south and north region was 5.82 and 4.34 per 10 000 births respectively. The difference between them is statistically significant (P〈0.05). The distribution of affected area between male and female was not significantly different (χ2 = 1.74,P〉0.05). Conclusion There was no increasing or decreasing trend on the prevalence of congenital clubfoot to be found in China during 2001 to 2010. The prevalence of congenital clubfoot in China was found with regional differences and gender differences. The prevalence of congenital clubfoot in Chinese population is greater than foreign populations.
出处 《四川大学学报(医学版)》 CAS CSCD 北大核心 2013年第4期606-609,共4页 Journal of Sichuan University(Medical Sciences)
关键词 先天性马蹄内翻足 发生率 出生缺陷监测 Congenital clubfoot Prevalence rate Birth defects monitoring
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