摘要
目的评估无创正压通气(non-invasive positive pressure ventilation,NIPPV)救治慢性阻塞性肺疾病(chronic ob-structive pulmonary disease,COPD)急性加重期合并呼吸衰竭患者的临床价值。方法 COPD合并Ⅱ型呼吸衰竭患者172例按随机数字表法分为观察组88例和对照组84例。两组均按照指南推荐的方法给予常规治疗,观察组在此基础上使用NIPPV治疗,对比分析两组患者的临床疗效及相关指标。结果与对照组相比,观察组患者治疗后的pH、PaO2、PaCO2等动脉血气指标明显改善,心率、呼吸频率显著降低,并趋于正常,病情好转率明显提高,住院天数及1年内再住院率减少,差异均具有统计学意义(P<0.05)。结论常规治疗基础上加用NIPPV治疗COPD合并Ⅱ型呼吸衰竭患者具有重要临床价值。
Objective To evaluate the clinical effect of non-invasive positive pressure ventilation（NIPPV） in the treatment of acute exacerbation of chronic obstructive pulmonary disease （AECOPD） with type H respiratory failure. Methods One hundred seven- ty two COPD patients with type H respiratory failure who were treated in our hospital during April 2010 to June 2012 were randomly di- vided into observation group and control group. The two groups were treated with conventional treatment. However, patients in the ob- servation group also received noninvasive ventilation. Results Compared to the control group, pH, Pa02, PaCO2 and other arterial blood gasses, as well as the heart rate and respiratory rate were significantly improved in the observation group. The condition improve- ment rate was higher and the hospital days were shorter in the observation group than that in the control group. All the differences be- tween the two groups were statistically significant （P 〈 0. 05 ）. Conclusions Noninvasive ventilation has a very important clinical ther-apeutic value for the AECOPD patients with type 11 respiratory failure.
出处
《实用医院临床杂志》
2013年第4期130-132,共3页
Practical Journal of Clinical Medicine
关键词
无创通气
呼吸衰竭
慢性阻塞性肺疾病
Non-invasive ventilation
Respiratory failure
Chronic obstructive pulmonary disease
