摘要
目的观察益气健脾方联合甲地孕酮治疗晚期癌症患者的疗效。方法将120例晚期癌症患者随机分为2组,对照组进行常规肠内、外营养维持,观察组给予益气健脾方+甲地孕酮治疗,观察两组患者的生活质量改善情况。结果观察组患者食欲改善率、体重改善率、KPS评分改善率分别为70.00%、48.33%、68.33%,均高于对照组的20.00%、10.00%、26.67%(P<0.01);观察组Ⅲ、Ⅳ级胃肠道反应发生率,Ⅲ、Ⅳ级骨髓抑制发生率分别为8.33%、5.00%,均低于对照组的23.33%、18.33%(P<0.05)。结论益气健脾方联合甲地孕酮治疗,可增强晚期癌症患者食欲,缓解其胃肠道反应,改善患者生活质量。
Objective To observe the effect of Qi-strengthening and Spleen-energy prescription combined with megestrol on patients with advanced cancer. Methods 120 cases of advanced cancer patients were randomly divided into two groups, control group was given routine enteral nutrition to maintain, while observation group was treated with Qi-strengthening and Spleen-energy prescription combined with megestrol, the improvement of life quality was ob- served. Results The improvement rate of appetite, weight, KPS score of observation group （ 70.00%, 48.33 %, 68.33 % ） were higher than those of control group （ 20. 00 % , 10. 00% ,26. 67 % ） （ P 〈 0. 01 ） ; Ⅲ and Ⅳ grade gastro- intestinal reaction rate, Ⅲ and Ⅳ grade bone marrow suppression rate of observation group （8.33% , 5.00% ） were lower than those of control group （ 23.33 % , 18.33 % ） （ P 〈 0.05 ）. Conclusion Qi-strengthening and Spleen-energy prescription combined with megestrol on advanced cancer can enhance the patient＇s appetite, alleviate gastrointestinal reactions and improve patients＇ quality of life.
出处
《实用药物与临床》
CAS
2013年第5期440-441,共2页
Practical Pharmacy and Clinical Remedies
关键词
晚期癌症
益气健脾方
甲地孕酮
生活质量
Advanced cancer
Qi-strengthening and Spleen-energy prescription
Megestrol
Quality of life
