摘要
目的分析人工流产(TOP)后生殖支原体(Mg)感染与盆腔炎(PID)的相关性,为临床预防和治疗流产后PID提供参考。方法以2007年3月-2012年3月医院收治的TOP患者为对象,筛查Mg和沙眼衣原体(CT)感染情况,单纯Mg感染的患者作为感染组,Mg和CT检测均阴性患者作为对照组;剔除发生CT感染的病例、随访资料不完整、患生殖器畸形和急、慢性疾病的病例;术后对所有患者随访6周,观察其术后PID的发病情况,分析Mg感染与人工流产术后PID发病率的相关性。结果 5年中共收集984例患者,其中Mg感染110例,感染率为11.18%,CT感染51例感染率为5.18%,同时感染Mg和CT的患者6例,感染率为0.61%,20～30岁年龄段感染率显著高于其他年龄段(P<0.01);随访发现Mg感染患者中出现PID共有15例,发病率为13.63%,而未感染患者中诊断为PID共有17例,发病率为3.53%;通过logistic回归分析可见总体在流产患者中Mg感染与PID的发病率差异有统计学意义(OR6.29,95%CI1.56～25.2),在药物流产患者中Mg感染与PID的发病率差异无统计学意义(OR8.68,95%CI 0.58～14.84),在手术流产患者中Mg感染与PID的发病率显著相关(OR5.78,95%CI1.02～32.80),手术流产后盆腔炎的发病率显著高于药物流产(P<0.01)。结论 Mg感染与手术流产后PID的发病率有显著相关性,推荐对手术流产患者进行Mg感染筛查并进行治疗,预防术后PID的发生。
OBJECTIVE To study the correlation between Mycoplasma genitaliurn （Mg） infections and pelvic inflammatory disease among women undergoing termination of pregnancy （TOP） so as to provide reference for prevention and treatment of pelvic inflammatory after TOP. METHODS All the case records of TOP that were performed at the hospital from Mar 2007 through Mar 2010 were analyzed. The Mg and Chlamydiatrachomatis （CT） infections were screened. The patients with Mg infections were assigned as the infection group, and the patients with Mg and CT tested negative were set as the control group. The cases with CT infections, inadequate data entered in the original logbook, genital malformations and acute or chronic diseases were excluded. A six- week follow-up was conducted after TOP to observe the incidence of all patients with PID. The correlation be-tween Mg and pelvic inflammatory after termination of pregnancy was analyzed. RESULTS A total of 984 TOPs were performed during the study period. One hundred and ten women were with Mg infections （11.18%） and 51 women were with CT infection （5.18%）, there were 6 cases mixed with Mg and CT infection , the infection rate was 0.61%. The infection rate of the patients aged between 20 and 30 years was significantly higher than that of other age groups of patients （P〈0.01）. The follow-up indicated that fifteen （13.63%） women with Mg infection had complications compatible with PID and were diagnosed with post-termination infection whereas only 3.53% among the women who were Mg and CT-negative controls were diagnosed with PID. This difference remained statistically significant by using logistic regression analysis （odds ratio OR 6.29, 95%CI 1.56-25.2）. Stratifying the women according to procedure into medical and surgical TOP, Mg remained an independent risk factor for PID in surgical TOP （OR 5.78, 95%CI 1.02-32.80） but not in medicine TOP （OR 8.68, 95%CI 0. 58-14. 84） ; the incidence of the pelvic inflammatory after the surgical TOP was significantly higher than that after the medicine TOP （P〈0.01）. CONCLUSION There is a significant correlation between the Mg infections and the pelvic inflam-matory after TOP, and the screening of Mg infections is recommended for the surgical TOP patients so to prevent the postoperative PID.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第11期2646-2648,共3页
Chinese Journal of Nosocomiology
关键词
生殖支原体
沙眼衣原体
盆腔炎
人工流产
Mycoplasma genitalium
Chlamydia trachomatis
Pelvic inflammatory
Termination of pregnancy
