摘要
目的分析引起老年恶性实体肿瘤患者医院感染的危险因素,减低医院感染率。方法回顾性分析2009年8月-2010年10月住院的460例老年恶性实体肿瘤患者,应用SPSS 17.0统计软件包对可能危险因素中正态分布的计量资料行t检验,对计数资料行χ2值检验,将两种检验中有统计学意义的因素进行多因素logistic回归分析,根据回归结果,按危险因素对感染影响的大小进行排列。结果 460例老年恶性实体肿瘤患者中,患呼吸道肿瘤、卡氏评分(KPS评分)、患低蛋白血症、TNM分期、中性粒细胞绝对计数及住院时间6个危险因素,经t检验、χ2检验差异有统计学意义;对6个因素进行多因素logistic回归分析,患呼吸道肿瘤、KPS评分<60分、患低蛋白血症、中性粒细胞绝对计数减少及住院时间延长均是医院感染危险因素。结论老年恶性实体肿瘤患者患呼吸道肿瘤是最主要的医院感染危险因素,应加强病房管理严格执行消毒隔离制度,预防医院感染的发生。
OBJECTIVE To analyze the risk factors of nosocomial infections in the senile patients with malignant solid tumors so as to reduce the incidence of nosocomial infections. METHODS A total of 460 cases of senile inpatients with malignant solid tumors, who were treated in the hospital from Aug 2009 to Oct 2010, were retrospectively analyzed. The SPSS 17. 0 statistical package was used to perform t-test and count column chi-square test for the normal distribution of measurement data. The multivariate logistic regression analysis was performed for the factors that had statistical significant. The risk factors were arranged according to their impact on the infections. RESULTS Of totally 460 senile patients with malignant solid tumors, the t-test and chi-square test showed that there was statistical difference in the respiratory tract tumors, KPS score, hypoproteinemia, TNM stage, the absolute neutrophil count, or duration of hospitalization; the multivariate logistic regression analsis of the six factors indicated that the respiratory tract tumors, KPS score less than 60 points, hypoproteine-mia, absolute neutrophil count decreased , and prolonged hospitalization were the risk factors of nosocomial infections. CONCLUSION Suffering from the respiratory tract tumors is the predominant risk factor of nosocomial infections in the senile patients with malignant solid tumors, it is necessary to strengthen the ward management and strictly implement the disinfection and isolation system so as to reduce the incidence of nosocomial infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第11期2578-2580,共3页
Chinese Journal of Nosocomiology
关键词
老年患者
恶性实体肿瘤
医院感染
危险因素
Senile patient
Malignant solid tumor
Nosocomial infections
Risk factors
