摘要
目的探讨电针刺激(electrical stimulation,ES)合谷穴对心房颤动的影响。方法 14只成年犬,麻醉后双侧第4肋间开胸,随机分为2组:7只犬单纯行心房快速起搏6 h为对照组;7只犬行心房快速起搏6 h中同时结合ES为实验组。在基础状态和每小时末测定心房和肺静脉各部位的有效不应期(effective refractory period,ERP)和心房颤动诱发窗口(atrial fibrillation window of vulnerability,AFWOV)。结果对照组中,心房快速起搏6 h导致各部位ERP逐渐降低,ERP离散度、AFWOV逐渐升高;ES实验组中,给予ES后抑制了心房快速起搏6 h所导致的ERP、ERP离散度和AFWOV的变化。结论 ES可抑制心房颤动的急性电重构。
Objective To investigate the inhibitory effects of electrical stimulation （ES） at ＂Hegu＂ Points on atrial fibrillation. Methods Fourteen adult dogs underwent intercostal thoracotomy at both sides after anesthesia. The dogs were randomly divided into two groups. The control group （n = 7） only received 6 hours of rapid aria1 pacing （RAP） and the ES group （n = 7） received 6 hours of RAP and concomitant ES. Effective refractory period （ERP） and atrial fibrilla- tion window of vulnerability （AFWOV） were measured at multiple atrial and pulmonary vein sites at the end of each hour. Results In the control group, ERP was progressively shortened, ERP dispersion and AFWOV dispersion was in- creased at all sites. In the ES group, 6-hour concomitant RAP ＋ ES did not induce any significant change in ERP and AF- WOV. Conclusion ES could suppress atrial fibrillation induced by rapid atrial pacing.
出处
《华南国防医学杂志》
CAS
2013年第6期383-385,共3页
Military Medical Journal of South China
基金
湖北省自然科学基金重点项目(2010CDA036)
关键词
电生理学
心房颤动
电重构
迷走神经刺激
Atrial fibrillation
Electrical remodeling
Electro-acupuncture
agus nerve stimulation
