摘要
目的探讨射频消融术(RFA)治疗肝脏恶性肿瘤的临床疗效。方法收集2006年1月至2010年1月间收治的259例肝脏恶性肿瘤患者资料,其中原发性肝细胞肝癌患者223例,肝转移癌患者36例。所有患者采用经皮穿刺RFA以及开腹RFA进行治疗,消融范围应超过瘤周约0.5～1.0cm。结果 RFA治疗1个月后,以CT增强扫描检查,其中肝细胞癌患者的消融率为97.3%,复发率为7.8%,严重并发症发生率为2.2%肝转移癌患者的完全消融率为98.6%,复发率为11.1%,严重并发症发生率为4.5%。治疗后,肝细胞癌患者的1、3、5年生存率分别为87.7%、55.3%和32.9%,其中61例Ⅰ期患者的1、3、5年生存率分别为97.6%、86.1%和47.0%;肝转移癌患者的生存时间为20.5个月(16～24个月)。结论射频消融用于治疗肝脏恶性肿瘤疗效确切,安全可靠,且并发症少,值得推广应用。
Objective To analyze the clinical curative effect of the radiofrequency ablation（RFA） in treatment of hepatic malignant tumors.Methods 259 patients with liver malignant tumor were collected in our hospital from January 2006 to January 2010,among them,223 with primary hepatocellular carcinoma patients,36 patients with liver metastases.All patients with percutaneous RFA and open RFA treatment, ablation area should be larger than the peritumoral about 0.5-1.0cm.Results After RFA treatment one month,with the enhanced CT scan,patients with hepatocellular cancer ablation rate was 97.3%,the recurrence rate was 7.8%,the rate of serious complications was 2.2%;and the complete ablation of cancer patients with liver metastasis rate was 98.6%,the recurrence rate was 11.1%,the incidence of serious complications was 4.5%.After the treatment of patients with hepatocellular carcinoma,1,3,5 year survival rates were 87.7%,55.3% and 32.9%,including 61 cases of stage I patient survival rates were 97.6%, 86.1% and 47%;liver metastasis survival of cancer patients was 20.5 months（16-24 months）.Conclusions The therapeutic effect of radiofrequency ablation for treatment of liver malignant tumors is effective, safe and reliable,and less complications,is worthy of popularization and application.
出处
《中国肿瘤临床与康复》
2013年第5期502-504,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
肝肿瘤
射频消融
临床疗效
Liver neoplasms Radiofrequency ablation Clinical effect
