摘要
目的 探讨影响神经母细胞瘤手术治疗的有关因素。方法 总结 16年中小儿神经母细胞瘤的治疗经验 ,着重对手术时机、手术方式等影响疗效的因素进行分析。结果 本组 10 8例中Ⅰ、Ⅱ期者仅占 12 .0 % (13/10 8) ;而Ⅲ、Ⅳ期者却占 87.9% (95 /10 8) ,其中Ⅲ期占 37.0 % (40 /10 8)、Ⅳ期占 5 0 .9% (5 5 /10 8)。手术组 88例 ,手术后 2年生存率Ⅰ期 10 0 %、Ⅱ期 81.8%、Ⅲ期 17.5 %、Ⅳ期14.3%。 8例延期手术完全切除肿瘤。结论 提高早期诊断率是改变预后的最直接方法 ,综合性手术治疗能显著提高进展期神经母细胞瘤的手术切除率。
Objective To search for factors affecting the surgical outcome of neuroblastoma in children. Methods The timing and methods of operation on neuroblastoma of 108 cases during the last 16 years were analyzed. Results At presentation, 13 cases belonged to stage Ⅰ and Ⅱ (12%), 40 cases belonged to stage Ⅲ (37%) and 55 cases to stage Ⅳ (51%). Among the 88 cases who underwent surgical treatment, the two-year survival rate was 100% in stage Ⅰ, 88.8% in stage Ⅱ, 17.5% in stage Ⅲ and 14.3% in stage Ⅳ. Complete tumor resection was performed on 8 cases by delayed primary excision. Conclusion An early diagnosis and adjunctive therapy are important to increase the resection rate and improve the prognosis of neuroblastoma in children.
出处
《中华小儿外科杂志》
CSCD
2000年第3期148-150,共3页
Chinese Journal of Pediatric Surgery
