摘要
目的观察头孢哌酮/舒巴坦治疗老年吸入性肺炎的临床疗效和不良反应,为临床治疗提供依据。方法回顾性分析2011年1月1日-2012年1月31日住院的41例老年患者吸入性肺炎应用头孢哌酮/舒巴坦治疗的临床疗效、细菌清除率及安全性。结果头孢哌酮/舒巴坦治疗老年吸入性肺炎总有效率为85.37%,细菌清除率为81.25%,不良反应发生率为9.76%。结论头孢哌酮/舒巴坦治疗老年吸入性肺炎效果良好且安全,是经验性治疗老年吸入性肺炎的首选药物之一。
OBJECTIVE To observe the clinical efficacy and adverse reactions of sulbactam-cefoperazone in the treatment of aspiration pneumonia in the elderly patients so as to offer evidence for the clinical treatment. METHODS A total of 41 cases of elderly patients with aspiration pneumonia who enrolled the hospital from Jan 1st 2011 to Jan 31st 2012 were selected as the study objects, the clinical efficacy, bacterial eradication rate and safety of sulbactam-cefoperazone were retrospectively analyzed. RESULTS The total effective rate of sulbactam-cefopera- zone in treatment of the aspiration pneumonia was 85.37%, the bacterial eradication rate was 81.25%, and the incidence of the adverse reaction was 9.76%. CONCLUSION Sulbactam-eefoperazone is effective and safe in the treatment of aspiration pneumonia in the elderly patients and should be used as the preferred antibiotics for the empirical treatment of aspiration pneumonia in the elderly patients.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第10期2454-2455,共2页
Chinese Journal of Nosocomiology
基金
温州市科技局资金资助(Y20100364)
关键词
头孢哌酮
舒巴坦
老年患者
吸入性肺炎
Sulbactam-cefoperazone
Elderly patient
Aspiration pneumonia
