摘要
目的:观察莫西沙星与左氧氟沙星治疗老年吸入性肺炎的临床疗效和安全性。方法:随机选择老年吸入性肺炎住院患者80例,分为治疗组和对照组,每组40例。治疗组使用莫西沙星400 mg静脉滴注给药,每日1次,对照组使用左氧氟沙星500 mg,静脉滴注给药,每日1次,共治疗7 d,观察2组疗效及不良反应。结果:治疗组和对照组的临床有效率分别为90.0%和82.5%,细菌清除率分别为94.3%和96.4%,不良反应发生率分别为15.0%和17.5%,2组各项指标差异均无统计学意义(P>0.05)。结论:莫西沙星针剂治疗吸入性肺炎疗效较佳,且安全有效。
Objective： To evaluate the efficacy and safety of moxifloxacin vs levofloxacin in the treatment of aspiration pneumonitis. Method： Forty cases with aspiration pneumonitis were enrolled as treatment group which was treated with moxifloxacin （400 mg iv qd for 7 d） and other 40 cases as control group with levo- floxacin （500 mg iv qd for 7 d）. Results： Results indicated that the total clinical effective rates of the treatment group and control group were 90% and 82. 50%, and the bacterial eradicanon rates 94. 29% and 96. 420% and the adverse effect rates 15% and 20%, respectively. No significant difference of the above figures between the two groups were found （P〉0.05 ）. Conclusion： Moxifloxacin was effective and safe in the treatment of aspiration pneumonitis.
出处
《新疆医科大学学报》
CAS
2008年第7期824-825,共2页
Journal of Xinjiang Medical University
