摘要
目的探讨利用红茶降低胃肠道液体对磁共振胰胆道成像(MRCP)干扰的可行性。方法研究分为3个部分:①体外试管试验:MRCP、T2-map及T1-map分别扫描15种不同饮料,得到最适合用于降低胃肠道对MRCP成像影响的饮料。②纳入10例健康志愿者,在口服饮料前及口服后5min、10min、15min进行MRCP扫描,得到最佳延迟时相。③纳入20例患者,在饮茶前及饮茶后5min进行MRCP扫描,测得胃、十二指肠、肝脏、胆总管、胰管、胆囊的信号值(SI)、信噪比(SNR)及喝茶前后胃、十二指肠的信号丢失,肝内胆管、肝管、胆总管、胰管、胆囊、胆胰壶腹部的图像质量改变。结果①体外试管试验显示最适用的饮料为立顿红茶。②健康志愿者试验发现,胃、十二指肠信号丢失的评价及胆道系统图像质量的评价在饮茶后5min、10min、15min之间差异无统计学意义(P>0.05)。③对患者的研究显示,饮茶前后胃、十二指肠的SI、SNR及信号的丢失,胆总管、胰管、胆囊及胆胰壶腹部的图像质量评价差异有统计学意义(P<0.05),但饮茶前后肝内胆管、肝管的图像质量,肝脏、胆总管、胰管、胆囊的SI及SNR差异无统计学意义(P>0.05)。结论作为一种简便、廉价、安全的饮料,立顿红茶能降低胃肠道液体对MRCP成像的干扰,可广泛应用于临床。
Objective To investigate the feasibility of using black tea as a gastrointestinal oral negative contrast agent to null the signal from fluid in bowel during MR cholangiopancreatography （MRCP）. Methods ① 15 different drinks were scanned with MRCP, T2-map and Tl-map in vitro to identify the most suitable drink for MRCP. ② 10 volunteers were scanned by MRCP prior to and 5, 10, 15 rain after tea consumptions to identify the optimal delay time. ③ 20 patients were scanned with MRCP prior to and 5 min after tea consumptions. The signal intensity （SI） and signal-to-noise ratio （SNR） of stomach, duodenum, liver-parenchyma, common bile duct （CBD）, pancreatic duct （PD） and gall bladder （GB） ; the singal loss of stomach and duodenum; and the image quality of ampulla of rater （AV）, intrahepatic ducts （IHD）, hepatic duct, CBD, PD and GB were analyzed with Siemens Workstation. Results ①Lipton black-tea was identified as the optimal drink in vitro. ② There were no significant differences in MRCP among the 3 delay times in volunteer tests. ③ The SI, SNR and SI loss of stomach and duodenum, and the image quality of CBD, PD, GB and AV showed a significant improvement of MRCP after tea consumptions （P〈0.05）. But tea consumptions made no significant differences in the image quality of IHD and hepatic duct, and the SI and SNR of liver, CBD, GB and PD （P〉0.05）. Conclusion As a simple, cheap and safe drink, black tea can be widely used to reduce signal intensity of gastrointestinal tract and provide improved image of MRCP.
出处
《四川大学学报（医学版）》
CAS
CSCD
北大核心
2013年第3期476-480,共5页
Journal of Sichuan University(Medical Sciences)
基金
成都市科技计划项目(No.12PPYB077SF-002)资助
关键词
磁共振胰胆道成像
红茶
胃肠道
对比剂
MR cholangiopancreatography Black tea Gastrointestinal tract Contrast
