摘要
目的研究不同手术术式对中晚期胰头癌姑息性手术的治疗效果。方法以本院接诊的41例中晚期胰头癌患者的临床资料进行回顾性分析,按照不同的术式分为3组,采取单纯胆囊空肠吻合术者共13例,采取肝(胆)总管空肠吻合术者共14例,采取胆肠吻合结合胃空肠吻合术者共14例,对比3组患者的30d死亡率、术后黄疸或者胆管炎复发率以及生存期。结果胆肠吻合结合胃空肠吻合术组术后生存期为(14.0±0.5)个月,死亡率为0,复发率为7.14%;单纯胆囊空肠吻合术组的生存期为(7.1±0.3)个月,死亡率为15.38%,复发率为61.53%;肝(胆)总管空肠吻合术组生存期为(10.3±0.3)个月,死亡率为7.14%,复发率为14.28%;3组比较,差异有统计学意义(P<0.05)。结论中晚期胰头癌姑息性手术应尽可能选择胆肠吻合结合胃空肠吻合术,疗效更好。
Objective To study the therapeutic effects of palliative operation of pancreatic head carcinoma in middle and advanced stages by different surgical methods. Methods The clinical data from 41 patients with pancreatic head carcinoma at middle and advanced stages admitted into our hospital were retrospectively analyzed. According to varied surgical methods, they were randomly divided into three groups： simple eholecystoenterostomy （SC） group （n = 13）, hepaticojejunostomy/choledochojejunostomy （H/C） group （n = 14）, and bilioenteric anastomosis combining with gastrojejunostomy （BACG） group （n = 14）. The indexes like mortality rate within 30 days, recurrence rate of jaundice or cholangitis after surgery, and life expectancy in these three groups were compared. Results The postoperative life expectancy in BACG group was （14.0±0.5） months, the mortality was 0, recurrence rate was 7.14%; in SC group with （7.1±0.3） months of life expectancy and mortality taking up 15.38%, recurrence rate was 61.53%; in H/C group that patients＇ postoperative life expectancy was （10.3±0.3） months, the mortality was 7.14%, recurrence rate was 14.28%. There were statistical differences among three groups （P 〈 0.05）. Conclusion The BACG is the optimum choice in treating palliative operation of pancreatic head carcinoma in middle and advanced stages for its better efficacy.
出处
《中国当代医药》
2013年第13期185-186,共2页
China Modern Medicine
基金
广东省科技计划项目(2008B030301177)
关键词
胰头癌
术式
胃肠转流
疗效
Pancreatic head carcinoma
Surgery option
Gastrointestinal bypass
Efficacy
