摘要
目的探讨胰头癌病人手术方式和临床病理特点对生存率的影响。方法研究对象为我院2000年1月至2009年1月有完整资料的38例胰头癌患者的临床资料、病理、随访资料进行研究,统计学分析。结果 1、3、5年累积存活率分别为67%、22%、14%。COX回归分析病变部位和病理分期对生存时间的影响有统计学意义。胰头癌不同部位起源的腹胰癌30%侵犯胆管,背胰癌全部侵犯胆管,二者间差异有显著意义(P=0.005)。腹胰癌Ⅱ、Ⅲ期和Ⅳ期分别为49%和51%,背胰癌为22%和78%(P=0.045)。不同病理分期的生存时间差异有统计学意义(P<0.05)。结论影响胰头癌生存期因素与癌在胰头部位有一定关系,背胰癌易较早胆总管、血管侵犯,淋巴转移,早期诊断早期根治性切除是治愈胰腺癌的重要基础。
Objective To explore the ways of pancreatic cancer surgery and the clinical pathological characteristics affecting survival rate.Methods The complete clinical data,pathology,follow-up data of 38 cases of pancreatic cancer patients in our hospital from January 2000 to January 2009 were studied and statistically analyzed.Results One-year,3-year,5-year cumulative survival rates were 67%,22%,14% respectively.COX regression analysis of the lesion and the pathological stage of the survival time was statistically significant.The origin of pancreatic cancer in different parts of the ventral pancreatic duct cancer,30% of the violations,all violations of dorsal pancreatic cancer,bile duct,the difference between the two was significant（P = 0.005）.Ventral pancreatic cancer stage Ⅱ,Ⅲ and Ⅳ was 49% and 51%,dorsal pancreatic cancer was 22% and 78%（P = 0.045）.The survival time of different pathological stages was significantly difference（P 0.05）.Conclusion The factors affecting survival rate of pancreatic cancer are related with cancer of pancreatic head;dorsal pancreatic cancer has earlier metastasis than common bile duct,vascular invasion,and lymph node.Early diagnosis and early radical resection is an important foundation to cure pancreatic cancer.
出处
《临床医学工程》
2011年第8期1234-1235,共2页
Clinical Medicine & Engineering
关键词
胰头癌
病理学
生存相关因素
Pancreatic cancer
Pathology
Survival factors
