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药物流产后异常子宫出血患者血清雌激素、孕激素和人绒毛促性腺激素水平 被引量:13

Estrogen,Progesterone,and Human Chorionic Gonadotrophin Levels in Patients with Abnormal Uterine Bleeding after Drug Abortion
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摘要 目的:研究药物流产后患者体内雌激素(E2)、孕激素(P)及人绒毛促性腺激素(hCG)水平与异常子宫出血的关系。方法:59例患者口服米非司酮配伍米索前列醇药物终止早期妊娠,将子宫出血时间超过14 d的30例患者作为异常子宫出血组,子宫出血时间少于14 d的29例患者作为对照组,比较2组外周静脉血清中E2、P及hCG水平。结果:两组患者体内E2差异无显著性(P>0.05),在出血第14天时,异常子宫出血组患者体内P明显高于对照组(P<0.05),在第14、18和22天hCG均高于对照组(P<0.05)。结论:药物流产后异常子宫出血与患者体内P和hCG水平有关。 Objective: To investigate the relationship of estrogen (E2), progesterone (P), and human chorionic gonadotrophin (hCG) levels with abnormal uterine bleeding in patients with drug abortion. Methods: A total of 59 patients taking mifepristone plus misoprostol for abortion were divided in- to two groups. In the control group (29 cases, group C), the time of uterine bleeding was less than 14 days; in the abnormal uterine bleeding (30 cases, group A), the time of uterine bleeding was more than 14 days. The levels of E2, P and hCG of the 2 groups in 14, 18 and 22 days after initiation of bleeding were compared. Results: There was no significant difference of E2 levels between the 2 groups ( P 〉 0.05 ) ; On the 14th day, P level of group A was higher than that of group C ( P 〈 0.05 ) ; On the 14th, 18th, and 22nd days, the hCG levels in group A were significantly higher than those in group C ( P 〈 0.05 ). Conclusion: The abnormal uterine bleeding in patients with medical abortion is related with P and hCG levels.
出处 《贵阳医学院学报》 CAS 2013年第2期149-151,共3页 Journal of Guiyang Medical College
关键词 流产 子宫出血 雌激素类 孕激素类 绒毛膜促性性腺激素 abortion uterine hemorrhage estrogens progestational hormone chorionie gonadotro-pin
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