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年轻妇女子宫内膜不典型增生的孕激素治疗——附36例分析 被引量:11

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摘要 目的分析孕激素治疗对年轻妇女子宫内膜不典型增生的疗效。方法36例年轻妇女子宫内膜不典型增生患者采用孕激素治疗后进行疗效评估。结果药物治疗3月后,总治愈率为80.6%(29/36),其中轻度子宫内膜不典型增生(EAH)治愈率为100.0%(14/14),中度为73.3%(11/15),重度为57.1%(4/7)。未好转者继续用药3月,其中4例中度EAH转化为萎缩期内膜,3例由重度EAH转化为中度EAH的病例转为分泌期或萎缩内膜,1例重度EAH病例继续用药6月后子宫内膜病变萎缩,治愈率达100.0%。但随诊2年后又有2例中度、2例重度EAH复发,1例重度EAH 3年后转为癌。结论对于年轻妇女子宫内膜不典型增生患者采用孕激素药物治疗安全有效,但需密切随访。
作者 韩君英
出处 《实用肿瘤杂志》 CAS 北大核心 2009年第3期283-285,共3页 Journal of Practical Oncology
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  • 1盖铭英 唐敏一 等.40岁以下妇女子宫内膜不典型增生的诊断和治疗[J].中华妇产科杂志,1981,16:48-51.
  • 2Bergeron C, Nogales FF, Masseroli M, et al. A multicentric European study testing the reproducibility of the WHO classfication of endometrial hyperplasia with a proposal of a simplified working classification for biopsy and curettage specimens. Am J Surg Pathol,1999,23(9) :1102.
  • 3Terakawa N, Kigawa J,Teretani AND, et al. The behavior of endometrial hyperplasia: a prospective study, endometrial hyperplasia study group. J Obstet Gynecol Head, 1997,23 ( 3 ) :223.
  • 4Tahir MM, Bigrigg MA, Browning JJ, et al. A randomised controlled trial comparing transvaginal ultrasound, outpatient hysteroscopy and endometrial biopsy with inpatient hysteroscopy and curettage. Br J Obstet Gynecol,1999,106( 1 ) :1259.
  • 5Jensen HH, Hussain SF, Pederson PH, et al. Atypical endometrial hyperplasia:prognosis and course. Ugeskr Laeger, 2000, 162 (5):666.
  • 6Randall TC, Kurman ILl. Pregestin treatment of atypical hyperplasia and well differentiated carcinoma of the endometrium in women under age 40_Obstet Gynecol, 1997,90(3 ) .434.
  • 7Kuman K J, Kaminski PF, Norris HJ. The behavior of endometrial hyperplasia:a long-term study of untreated hyperplasia in 170 patients.Cancer, 1985,56 ( 2 ) :403.
  • 8Ferenczy A, Gelfand M. The biologic significance of cytologic atypic in progestin-treated endometrial hyperplasia. Am J Obstet Gynecol,1989,160( 1 ) :126.
  • 9Amezcua CA, Zheng WX, Muder Spach LI, et al. Down regulation of Bcl-2 is a potential marker of the efficacy of progestin therapy in the treatment of endometrial hyperplasia. Gynecol Oncol, 1999,73(1) :126.
  • 10Mutter GL. Endometrial intraepithelial neoplasia ( EIN ) : will it bring order to chaos? Gynecol Oncol,2000,76( 3 ) :289.

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