摘要
蛋白质与核酸的序列分析在现代生物学和生物信息学中发挥着重要作用 ,新的算法和软件层出不穷 ,本文介绍一个可运行在PC机上的完全免费的多序列比较软件 ClustalW ,它不但可以进行蛋白质与核酸的多序列比较 ,分析不同序列之间的相似性关系 ,还可以绘制进化树。由于其灵活的输入输出格式、方便的参数设定和选择、详尽的在线帮助以及良好的可移植性 ,使得ClustalW在蛋白质与核酸的序列分析中得到了广泛应用。
The sequence analysis of protein and nucleic acid is important in the modern biology and bioinformation. In this article I introduce a free multiple sequence alignment software?Clustal W which can run on personal microcomputer. This software can deal with the protein or nucleic acid multiple sequence alignment, analyze the similarly relation of different sequence and draw phylogenetic trees. Clustal W is widely used on the sequence analysis of protein and nucleic acid for its agility, convenient and transportable character.
出处
《生物技术通讯》
CAS
2000年第2期146-149,共4页
Letters in Biotechnology
