摘要
目的研究鹅绒藤(Cynanchum chinense R.Br.)地上部位的化学成分。方法采用AB-8大孔树脂柱,硅胶柱色谱,LX2000树脂柱,Sephadex LH-20柱色谱等方法分离纯化;利用核磁共振波谱技术鉴定化合物结构。结果从鹅绒藤地上部位70%乙醇提取物中分离得到9个化合物,分别鉴定为十六烷酸(Ⅰ)、水杨酸(Ⅱ)、β-谷甾醇(Ⅲ)、β-胡萝卜苷(Ⅳ)、芹菜素(Ⅴ)、山奈酚(Ⅵ)、山奈酚-3-O-β-D-吡喃葡萄糖苷(Ⅶ)、小麦黄素(Ⅷ)、小麦黄素-7-O-β-D-葡萄糖醛酸苷(Ⅸ)。结论化合物Ⅴ、Ⅷ、Ⅸ为首次从本属植物中分离得到;化合物Ⅰ、Ⅱ、Ⅴ～Ⅸ为首次从本植物中分离得到。
OBJECTIVE To study the chemical constituents of the aerial parts of Cynanchum chinense R. Br. METHODS The compounds were extracted and purified by AB-8 macroporous resins, silica gel column chromatography, LX2000 resin and Sephadex LH-20 columns. Their structures were elucidated on the basis of physico-chemical properties and NMR spectral analysis. RESULTS Nine compounds were obtained from 70% aqueous ethanol extract of Cynanchum chinense and elucidated as n-hexadecanioc acid （Ⅰ）, salicylic acid （Ⅱ）, β-sitosterol （Ⅲ）, β-sitosterolglucoside （Ⅳ）, apigenin （Ⅴ）, kaemperol （Ⅵ）, kaemperol-3-O-β-D-glunoside （Ⅶ）, tricin （Ⅷ）, and tricin-7-O-β-D-glucuronide （Ⅸ）. CONCLUSION Compounds Ⅴ, Ⅷ and Ⅸ were obtained from this genus, and compounds Ⅰ, Ⅱand Ⅴ-Ⅸ were isolated from this plant for the first time.
出处
《中国现代应用药学》
CAS
CSCD
2013年第3期274-277,共4页
Chinese Journal of Modern Applied Pharmacy
