摘要
目的探讨益赛普、柳氮磺吡啶联合功能锻炼治疗强直性脊柱炎的临床疗效。方法选取2010年7月～2012年7月在我院确诊为强直性脊柱炎的70例患者，随机分为观察组和对照组各35例。对照组仅采用益赛普和柳氮磺吡啶用药来进行治疗，观察组在对照组用药的基础上配合功能锻炼来对强直性脊柱炎进行治疗，治疗3个月为1个疗程，治疗后对两组进行对比分析。结果患者经过1个疗程的治疗后，两组患者临床症状均有不同程度的缓解；但观察组总体有效率明显高于对照组，两组间比较差异有统计学意义（P〈0．05）。结论益赛普、柳氮磺吡啶联合功能锻炼对强直性脊柱炎的治疗有确切的临床效果，且安全性较好，不良反应少，值得在临床进一步推广应用。
Objective To investigate the clinical efficacy of etanercept,sulfasalazine combined with functional exercise in the treatment of ankylosing spondylitis. Methods Seventy patients diagnosed with ankylosing spondylitis in our hospital from July 2010 to July 2012 were randomly divided into the observation group and the control group,with 35 patients in each group. The control group only received etanercept and sulfasalazine medication and the observation group received additional functional exercise on the basis of the control group. One treatment course consisted of 3 months. The two groups were compared and analyzed after treatment. Results After l treatment course,elinica｜ symptoms of the two groups relieved to varying degrees;But the observation group was significantly higher than the control group in the total effective rate,with statistically significant difference between the two groups （P 〈 0.05）. Conclusion Etanercept,sulfasalazine combined with functional exercise shows accurate clinical efficacy,good safety and few adverse reactions in the treatment of ankylosing spondylitis,thereby worth further clinical promotion and application.
出处
《中国医药科学》
2013年第6期82-83,共2页
China Medicine And Pharmacy
关键词
益赛普
柳氮磺吡啶
功能锻炼
强直性脊柱炎
Etanercept
Sulfasalazine
Functional exereise
Ankylosing spondylitis
