摘要
目的 :评价艾灸神阙穴在Ⅲ、Ⅳa期鼻咽癌放化疗中的作用及疗效。方法 :56例患者随机均分为两组 ,两组放疗均采用常规方法 ,化疗采用AD方案。治疗组在放化疗开始时行隔盐艾灸神阙穴 ,30次为 1个疗程。结果 :放化疗治疗结束后 ,两组患者鼻咽肿瘤消退率差异无显著性 ,毒副反应治疗组较对照组低 (P <0 0 5) ;5年的鼻咽肿瘤和淋巴结局部控制率治疗组为 85 7%和 85 0 % ,对照组为 78 6%和 78 9% ;5年生存率治疗组和对照组分别为 50 0 %和 35 7%。治疗组治疗后血浆丙二醛、中分子物质含量明显降低 ,血浆总巯基含量、超氧化物歧化酶活性升高 ,与对照组比较差异均有显著性 (P <0 0 5,P <0 0 1)。结论 :艾灸神阙穴能明显减轻Ⅲ。
Objective: To evaluate the effect of supplementary moxibustion in treating Ⅲ、Ⅳa stage nasopharyngeal carcinoma (NPC) with radio and chemotherapy. Methods: Fifty six cases of NPC were randomly divided into two groups, 28 in each group. They were treated with radiotherapy in routine or chemotherapy adopting AD protocol. Salt separated moxibustion on Shenque (Ren 8) point was given to the treated group from beginning of radio and chemotherapy for 30 times as one therapeutic course. Results: The remission rate in the two groups after radio and chemotherapy was not different significantly. The toxic and side effect occurrence was less in the treated group than that in the control group (P<0 05). The 5 year local control rates of NPC and cervical lymphnode were 85.7% and 85.0% in the treated group, which were higher than those in the control group ( 78.6% and 78.9%). The 5 year survival rate in the two groups were 50.0% and 35.7% respectively. After radio and chemotherapy, the blood content of malonyldialdehyde (MDA), middle molecular substance and sulfhydryl reduced the SOD activity ascended in the treated group, the difference was significant as compared with those in the control group (P<0 05, P<0 01). Conclusion: The supplementary moxibustion on Shenque point could obviously reduce the toxic side effect of advanced NPC patients treated with radio and chemotherapy
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2000年第10期733-735,共3页
Chinese Journal of Integrated Traditional and Western Medicine
基金
军队科研基金资助课题!(No .910106)
关键词
鼻咽癌
艾灸
毒副作用
神阙穴
放射疗法
nasopharyngeal carcinoma, moxibustion, toxic side effect, survival rate, lipid peroxide
