摘要
目的:观察梅花针治疗卵泡发育不良的临床疗效。方法:将50例卵泡发育不良的患者随机分为梅花针组和药物组,每组25例。梅花针组在卵泡生长期采用梅花针循经叩刺任、督、带脉,以及脾俞、胃俞、肾俞和卵巢、子宫穴,隔日治疗1次;药物组采用口服氯米芬(CC)及肌内注射人绒膜促性腺激素(HCG)进行治疗,每天1次。两组均以1个月经周期为一疗程,治疗2个疗程后,比较两组的卵泡发育情况、子宫内膜厚度及形态变化、卵巢动脉血流阻力指数(RI)和搏动指数(PI)、排卵率和妊娠率。结果:治疗后,两组患者最大卵泡平均直径均有所增加,且梅花针组子宫内膜形态及厚度改变优于药物组(均P<0.05)。成熟卵泡期梅花针组卵巢动脉血流阻力指数、搏动指数均低于药物组(均P<0.05)。两组治疗后的排卵率和妊娠率差异无统计学意义(均P>0.05)。结论:梅花针治疗卵泡发育不良能增强患者的卵巢血流灌注,促进卵泡生长发育,提高成熟卵泡排卵率,疗效优于西药,并能避免西药治疗中卵泡生长与子宫内膜生长不同步的缺点。
Objective To observe clinical efficacy of plum-blossom needle for follicular maldevelopment （FM）. Methods Fifty cases of FM were randomly divided into a plum-blossom needle group and a medication group, 25 cases in each one. In the plum-blossom needle group, the plum-blossom needle was applied along Thoroughfare , Conception, Governor and Belt Vessel as well as at Pishu （BL 20）, Weishu （BL 21）, Shenshu （BL 23）, Luan- chao （Extra）, Zigong （EX-CA 1） during the follicular growth phase, once every other day. In the medication group, clomifene （CC） was prescribed for oral administration and human choriogonadotropin （HCG） was given by intramuscular injection, once each day. For both groups, one menstrual cycle constituted one course. After two courses of treatment, follicular development condition, the changes of endometrial thickness and morphology, ovarian resistent index （RI） and pulsatility index （PI）, rate of ovulation and pregnancy were compared between the two groups. Results After the treatment, the average diameters of the biggest follicle increased in both groups, while the endometriai thickness and morphology in the plum-blossom needle group were superior to those in the medication group （all P^0.05）. Ovarian RI and PI during mature follicular phase in the plum-blossom needle group were inferior to those in the medication group （both P^O. 05）. The differences in ovulation and pregnancy rate were not significant statistically between the two groups （both P〉O. 05）. Conclusion The plum-blossom needle therapy based on regulating Thoroughfare, Conception, Governor and Belt Vessel could improve the ovarian blood perfusion, promote the follicular growth, increase the ovulation rate of mature follicle and avoid the out-of- sync between growth of follicle and endometrium during the treatment of western medication.
出处
《中国针灸》
CAS
CSCD
北大核心
2013年第3期213-217,共5页
Chinese Acupuncture & Moxibustion
基金
国家中医药管理局全国名老中医传承工作室建设项目:1199ws 02
广东省中医院中医特色与优势临床研究专项课题:092YTS 14
关键词
卵泡发育不良
梅花针疗法
绒毛膜促性腺激素
随机对照试验
follicular maldevelopment
plum-blossom needle therapy choriogonadotropin randomized con-trolled trial （RCT）
