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联合抗幽门螺旋杆菌治疗对冠心病疗效的影响 被引量:1

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摘要 目的观察抗幽门螺旋杆菌(Helicobacter pylori,HP)治疗对冠心病临床疗效的影响。方法冠心病并HP感染患者120例随机分为治疗组和对照组各60例,对照组给予扩张冠状动脉、抗凝、调脂、平稳血压、纠正心力衰竭、营养心肌等常规治疗,治疗组在对照组治疗基础上给予标准方案抗HP治疗14d。比较2组治疗前、治疗后14d血清总胆固醇(total cholesterol,TC)、三酰甘油(triacylglycerol,TG)、低密度脂蛋白胆固醇(low density lipoprotein-cholesterol,LDL-C)、血浆纤维蛋白原(fibrinogen,FIB)水平及有效率,随访观察6个月内严重心、脑血管事件发生情况及因冠心病再住院情况。结果 2组治疗后TC,TG,LDL-C,FIB水平均较治疗前降低(P<0.05),治疗组TC,LDL-C,FIB水平较对照组明显下降(P<0.05);治疗组有效率(90%)高于对照组(60%)(P<0.05);随访观察6个月,治疗组严重心、脑血管临床事件发生率及再住院率低于对照组(P均<0.05)。结论积极抗HP治疗可提高冠心病患者治疗有效率,降低短期内再住院率,改善患者预后。
出处 《中华实用诊断与治疗杂志》 2013年第3期278-280,共3页 Journal of Chinese Practical Diagnosis and Therapy
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