摘要
目的:探讨抗幽门螺旋杆菌治疗对冠心病疗效的影响。方法:对收治我科的冠心病病人常规做尿素酶试验,将尿素酶试验阳性的患者随机分为A组(治疗组)、B组(对照组),两组患者均给予冠心病常规治疗,A组患者加用抗幽门螺旋杆菌治疗。治疗前后观察两组患者的超敏C反蛋白(hs-CRP)、甘油三酯(TG)、纤维蛋白原(FIB)变化,并观察两组患者的冠心病症状缓解情况及半年内的冠心病再住院率。结果:A组患者的hs-CRP、TG、FIB较治疗前显著下降,且显著优于对照组(P均<0.05),而B组患者则变化不明显;A组患者总有效率(96.5%)显著高于对照组(72.98%),半年内因冠心病再住院率(10.29%)显著低于B组(20.97%,P<0.05)。结论:积极抗幽门螺旋杆菌可显著提高冠心病治疗的有效率,并降低其短期内冠心病的再住院率。
Objective： The study the effect of treat helicobacter pylori on coronary heart disease （CHD）. Methods： The patient with coronary heart disease （CHD） were routinely performed urease test. All the CHD patient with positive result of urease test were randomly divided to therapy group （65 cases, treated with routine and helicobacter pylori therapy） and control group. （64 cases, treated only with routine therapy）. After treatment the symptom and sixmonth CHD hospitalization rate of two groups were observed and TG, hs--CRP, FIB concentrations were detected. Results： The TG, hs--CRP and FIB of group A were significantly reduced, and more reduced than those of group B （P〈0.05 all） ; those of group B were not obvious changes. Six-month CHD hospitalization rate of group A （10.29 % ） was significantly lower than that of group B （20.97%, P〈0.05）. Conclusion： Helicobacter pylori infection may be related with coronary heart disease.
出处
《心血管康复医学杂志》
CAS
2009年第6期584-586,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
螺杆菌
幽门
冠状动脉疾病
治疗
Helicobacter pylori
Coronary artery disease
Therapy
