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血糖达标与ACCORD临床研究关系的研讨 被引量：1

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摘要 糖尿病是以糖代谢障碍为主的常见多发代谢病,其患病率从改革开放前的1%升高到现今的9.7%,翻了近十倍。在年20岁以上几乎每十人中可有1名糖尿病,绝大多数为2型糖尿病,在老年人中几乎每五人中可有1名糖尿病。糖尿病前期即有糖调节障碍（impaired glucose regulation,IGR）,包括空腹血糖受损（IFG）,
作者 陈家伟
机构地区 南京医科大学第一附属医院(江苏省人民医院)
出处 《实用糖尿病杂志》 2013年第1期3-4,共2页 Journal of Practical Diabetology
关键词 血糖达标 临床研究 2型糖尿病 空腹血糖受损 糖代谢障碍 糖尿病前期 调节障碍 代谢病
分类号 R587.1 [医药卫生—内分泌]
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参考文献6

  • 1Gerstein HC,Miller ME,et al.Long-term effects of intensive glucose lowering on cardiovascular outcomes[].The New England Journal of Medicine.2011
  • 2Nyenwe EA,Jerkins TW,Umpierrez GE, et al.Management of type 2 diabetes: evolving strategies for the treatment of patients with type 2 diabetes[].Metabolism.2011
  • 3Ginsberg HN,Elam MB,Lovato LC,et al.Effects of combination lipid therapy in type2diabetes mellitus[].The New England Journal of Medicine.2010
  • 4Buse JB,Bigger JT,Byington RP,et al.Action to Control Car-diovascular Risk in Diabetes (ACCORD)trial:design and methods[].The American Journal of Cardiology.2007
  • 5The ACCORD Study Group.Effects of intensive blood pressure control in type 2 diabetes mellitus[].The New England Journal of Medicine.2010
  • 6Inzucchi SE,Nauck M,Bergenstal RM,et al.Management of hyper glycemia in type 2 diabetes:A patient-centered approacb.Posi-tion statement of the ADA and the EASD[].Diabetes Care.2012

同被引文献15

  • 1Phillip K, Bo W, Rosemarle M, et aI. Diabetes Complication: The microRNA perspective. Diabetes,2011,601832-1837.
  • 2Shawn SB, Farhad RD. Managing microvascular complications of diabetes with microRNAs. J Am Soc Nephrol, 2012,2a.. 185- 187.
  • 3Wu J H, Gao Y, Ren AJ, et al. Altered microRNA expression profiles in retinas with diabetic retinopathy. Ophthalmic Res, 2011,47 : 195-201.
  • 4McArthur K, Feng B, Wu Y, et al. MieroRNA-200b regulates vascular endothelial growth factor-mediated alterations in dia- betic retinopathy. Diabetes, 2011,60 : 1314-1323.
  • 5Lucrecia AM, Johanna KD, The role of non-coding RNAs in dia betie nephropathy:Potential applications as biomarkers or dis ease development and progression. Diabetes Res Clin Pract 2013,99: 1-11.
  • 6Wang B, Komers R, Carew R, et al. Suppression of microRNA- 29 expression by TGF -131 promotes collagen expression and re- nal fibrosis. J Am Soc Nephrol,2012,23 ..252-265.
  • 7Qin W, Chung AC, Huang XR, et al. TGF-/Smad3 signaling promotes renal fibrosis by inhibiting miR-29. J Am Soc Neph- rol, 2011,22 : 1462-1474.
  • 8Mitsuo K,Laura A,Wang M, et al. A microRNA circuit medi- ates transforming growth factor- 1 autoregulation in renal glo- merular mesangial cells. Kidney Int, 2011,80 .. 358-368.
  • 9Kovaes B, Lumayag S, Cowan C, eta[. microRNAs in early dia- betic retinopathy in streptozotocin-induced diabetic rats. Invest Ophthalmol Vis Sci, 2011,52 : 4402-4409.
  • 10Long J, Wang Y. MieroRNA-29c is a signature microRNA un- der high glucose conditions that targets sprouty homolog 1,and its in vivo knockdown prevents progression of diabetic nephrop- athv. 1 Biol Chem. 2011. 286 , 11837-11848.

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实用糖尿病杂志
2013年 第1期

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