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生活方式干预对糖尿病前期患者的效果观察 被引量:18

Effect of Intensive Lifestyle Intervention on Patients with Pre-Diabetes in Community
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摘要 目的:分析对糖尿病前期患者进行社区干预的效果。方法:按照中国2型糖尿病防治指南中的标准,对上海市松江区某社区≥45岁的糖尿病高危人群进行筛查,并将其中自愿参加干预的162名糖尿病前期(impaired glucose regulation,IGR)患者随机分为两组:强化干预组(n=81)和对照组(n=81),前者接受强化教育和干预;后者只接受常规的健康教育。结果:干预1年后,两组吸烟率显著降低;强化干预组空腹血糖比对照组多下降了0.41mmol/L,且收缩压均值低于对照组;强化干预组的糖尿病转化率较对照组低16%(P<0.05)。结论:应对糖尿病前期人群积极进行健康教育,使其改变不良的生活方式,减少糖尿病的发生。 Objective:To evaluate the effect of community-based intensive lifestyle intervention on patients with pre-diabetes. Methods: According to the screening standard in Chinese guideline for type 2 diabetes mellitus (DM), the high risk residents aged ≥45 in Songjiang District of Shanghai were screened and investigated. A total of 162 volunteers with impaired glucose regulation (IGR) were allocated randomly either into the intensive intervention group or the control group. Participants in in- tensive intervention group received intensive health education and lifestyle intervention, while those in the control group only received the routine health education. Results: After one-year follow-up, although the smoking rate and the drinking rate de creased significantly in both groups, the fasting blood glucose (FBG) showed a more drastic decrease in the intensive interven- tion group than that in the control group, and the average systolic blood pressure was lower in the intensive intervention group than that in the control group. The rate of IGR converting into diabetes was 16% lower in the intervention group than that in the control group (P〈0.05). Conclusions: It is necessary for the patients with IGR to receive health education to help them to rectify unhealthy lifestyle, in order to reduce the chance to develop to DM.
作者 宋丽娟 王伟
出处 《中国临床医学》 2012年第4期422-423,共2页 Chinese Journal of Clinical Medicine
基金 上海市松江医学领先专业项目(编号:09-II-32)
关键词 糖尿病前期 生活方式 干预 Impaired glucose regulation Lifestyle Intervention
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  • 1马学毅.糖尿病诊断治疗学[M].北京:人民军医出版社,2007:68-72.
  • 2Tuomilehto J? Lindstr MJ, Eriksson JG,et al. Prevention oftype 2 diabetes mellitus by changes in life style among sub-jects with impaired glucose tolerance [J]. N Engl J Med,2001, 344 (18):1343-1350.
  • 3Knowler WC,Barrett-Connor E,Fowler SE,et al . Reduction inthe incidence of type 2 diabetes with life style intervention or met-formin [J]. N Engl J Med, 2002,346(6) :393-403.

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