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Hedgehog信号通路与胰腺癌 被引量：2

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摘要 胰腺癌是人类最难治愈的致死性恶性疾病之一，5年生存率不到5％，在美国，胰腺癌居癌症相关死亡的第四位。造成临床预后较差的部分原因是胰腺癌发生、发展过程中的机制尚未完全清楚。Hedgehog（Hh）信号通路是胚胎发育的主要调控子，其产物控制细胞分化、组织成形和细胞增殖。在成人正常组织中Hh信号通路已无表达或低表达。
作者 马丹 高军 李兆申
机构地区 第二军医大学长海医院消化内科
出处 《中华胰腺病杂志》 CAS 2013年第1期63-67,共5页 Chinese Journal of Pancreatology
关键词 HEDGEHOG信号通路 胰腺癌 正常组织 5年生存率 恶性疾病 临床预后 胚胎发育 细胞分化
分类号 R735.9 [医药卫生—肿瘤]
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参考文献34

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共引文献3

同被引文献40

  • 1王玉琼,高军,李兆申.胰腺癌中Hedgehog通路与其他通路间相互作用的研究进展[J].中国肿瘤生物治疗杂志,2015,22(1):112-115. 被引量：2
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中华胰腺病杂志
2013年 第1期

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