摘要
目的对Sysmex CA1500全自动血凝仪纤维蛋白原测定方法 Von Clauss法和PT-der法的应用进行比较评价。方法对门诊及住院患者167例标本同时用Von Clauss法和PT-der法测定,将结果按PT-der法测定的纤维蛋白原(FIB)含量分为3个水平组进行比较,并进行统计学分析。结果对PT-der法与Von Clauss法测定FIB含量进行比较,当FIB浓度在2.0～4.0g/L时,两组结果差异无统计学意义(P>0.05)。当FIB>4.0g/L或<2.0g/L时,差异有统计学意义(P<0.05)。结论 Von Clauss法准确性高,特异性强,快速简便,但试剂昂贵,而PT-der法不需另行独立测定,可节约试剂成本。实验室可将两种方法结合,这样既能保证结果的准确性,又保证检测速度,提高工作效率,节约成本。
Objective To evalute two different methods of fibrinogen assay by the automatic coagulometer of Sysmex CA1500.Methods Von Clauss method and PT-der method were used to detect 167 clinical samples.FIB was divided into 3 groups based on the results of PT-der method.The result of FIB was analyzed by statistical method.Results Compare with two methods of PT-der and Von Clauss,there was not statistically significant difference（P0.05） when the concentration of fibrinogen was between 2.0-4.0 g/L.When the concentration of fibrinogen was lower than 2.0 g/L or higher than 4.0 g/L,the two methods had statistically significant difference（P0.05）.Conclusion Von Clauss has high veracity,it is a fast and simple method,but the reagent is very expansive.PT-der method don＇t any reagent,so the cost is low.The combination of the two methods can make sure that works are good quality and rapid,improve efficiency,and reduce the reagent cost.
出处
《检验医学与临床》
CAS
2013年第1期43-44,共2页
Laboratory Medicine and Clinic
