摘要
目的观察雷贝拉唑联合阿莫西林、甲硝唑治疗十二指肠溃疡(DU)及根除幽门螺杆菌(Hp)的疗效。方法将50例Hp阳性的DU患者随机分为治疗组及对照组,治疗组给予雷贝拉唑、阿莫西林、甲硝唑,对照组给予奥美拉唑、阿莫西林、甲硝唑。4周后复查胃镜及14C呼气试验,观察溃疡愈合以及Hp根除情况。结果治疗组及对照组DU愈合率差异有统计学意义(P<0.05),Hp根除率差异无统计学意义(P>0.05)。结论雷贝拉唑相对于奥美拉唑在治疗DU时有更好疗效。
Objective To observe the curative effect of duodenal ulcer （DU） treating and Hp eradication with Rabeprazole, Amoxicillin and Metronidazole. Methods Fifty cases of DU with positive Hp were randomly divided into treatment group and control group. For treatment group, they were given Rabeprazole, Amoxicillin and Metronidazole. For control group, they were given Omeprazole, Amoxicillin and Metronidazole. Four weeks later, the union of ulcer and the eradication of Hp by gastroscopy and 14C breathing test were observed. Results There was obvious difference between treatment group and control group on DU union rate （P 〈 0.05）, and no obvious difference on the eradication rate （P 〉 0.05）. Conclusion Rabeprazole is more curative than omeprazole on DU treatment.
出处
《中国当代医药》
2013年第4期83-84,共2页
China Modern Medicine
