摘要
目的观察孟鲁司特治疗毛细支气管炎的疗效和预防喘息反复发作的效果。方法将2009年1月—2011年6月我科住院的呼吸道合胞病毒毛细支气管炎患儿100例随机分为两组,每组各50例。两组均给予常规治疗,治疗组加用孟鲁司特口服至症状及体征消失后1周,随访1年。结果治疗7d后两组疗效比较差异有统计学意义(P<0.05);且喘息反复发作病例数低于对照组,差异有统计学意义(P<0.01)。结论孟鲁司特治疗毛细支气管炎疗效显著,能预防喘息反复发作。
Objective To study the effect of Montelukast in respiratory syncytial virus(RSV)bronehiolitis and to evaluate the efficiency of montelukast indecreasing the incidence of asthma following broehiolitis.Methods Methods From Jan,2010 to June,2011,100 cases who were diagnosed RSV bronchiolitis were divided in two groups,therapy group 50cases and control group 50 cases.Conventional Medical treatment were given in two groups,and montelukast was givent in therapy group additionally.The time of follow up was over l year. Results The effect rate of therapy group was significant higher than control group(P0.05).The patients with frequent asthma attack following brochiolitis in therapy group waere less than those in control gruop(P0.05). Conclusion Montelukast can improve the therapy effects of RSV bronchiolitis and decrease the incidence of asthma following brochiolitis.
出处
《临床合理用药杂志》
2012年第36期3-4,共2页
Chinese Journal of Clinical Rational Drug Use